Speech timing and monosyllabic diadochokinesis measures in the assessment of amyotrophic lateral sclerosis in Canadian French.

The primary objective of this study was to determine if speech and pause measures obtained using a passage reading task and timing measures from a monosyllabic diadochokinesis (DDK) task differ across speakers of Canadian French diagnosed with amyotrophic lateral sclerosis (ALS) presenting with and...

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Published in:International Journal of Speech-Language Pathology Vol. 26; no. 2; pp. 267 - 278
Main Authors: Bouvier, Liziane, McKinlay, Scotia, Truong, Justin, Genge, Angela, Dupré, Nicolas, Dionne, Annie, Kalra, Sanjay, Yunusova, Yana
Format: research tables/charts Journal Article
Published: Taylor & Francis Ltd Apr2024
Online Access:View this record in EBSCOhost
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      dt: Apr2024
      vid: 26
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      pub: Taylor & Francis Ltd
      place: Philadelphia, Pennsylvania
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        10.1080/17549507.2023.2214706
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        atl: Speech timing and monosyllabic diadochokinesis measures in the assessment of amyotrophic lateral sclerosis in Canadian French.
      aug:
        au:
          Bouvier, Liziane
          McKinlay, Scotia
          Truong, Justin
          Genge, Angela
          Dupré, Nicolas
          Dionne, Annie
          Kalra, Sanjay
          Yunusova, Yana
        affil: School of Communication of Sciences and Disorders, Department of Medicine and Health Sciences, University of Toronto, Montreal, QC, Canada
      sug:
        subj:
          Amyotrophic Lateral Sclerosis Diagnosis
          Speech Production Measurement Evaluation
          Bulbar Palsy, Progressive Symptoms
          Teaching Materials
          Severity of Illness Evaluation
          Education, Continuing
          French Canadians
          Human
          Middle Age
          Male
          Female
          Canada
          Secondary Analysis
          Descriptive Statistics
          Age Factors
          Speech Rate
          Comparative Studies
          Control Group
          Correlational Studies
          Early Diagnosis
          Speech Disorders
          Speech Evaluation
          Dysarthria
          Kruskal-Wallis Test
          Post Hoc Analysis
          Funding Source
          Middle Aged: 45-64 years
          Male
          Female
      ab: The primary objective of this study was to determine if speech and pause measures obtained using a passage reading task and timing measures from a monosyllabic diadochokinesis (DDK) task differ across speakers of Canadian French diagnosed with amyotrophic lateral sclerosis (ALS) presenting with and without bulbar symptoms, and healthy controls. The secondary objective was to determine if these measures can reflect the severity of bulbar symptoms. A total of 29 Canadian French speakers with ALS (classified as bulbar symptomatic [n = 14] or pre-symptomatic [n = 15]) and 17 age-matched healthy controls completed a passage reading task and a monosyllabic DDK task (/pa/ and /ta/), for up to three follow-up visits. Measures of speaking rate, total duration, speech duration, and pause events were extracted from the passage reading recordings using a semi-automated speech and pause analysis procedure. Manual analysis of DDK recordings provided measures of DDK rate and variability. Group comparisons revealed significant differences (p = <.05) between the symptomatic group and the pre-symptomatic and control groups for all passage measures and DDK rates. Only the DDK rate in /ta/ differentiated the pre-symptomatic and control groups. Repeated measures correlations revealed moderate correlations (rrm = > 0.40; p = < 0.05) between passage measures of total duration, speaking rate, speech duration, and number of pauses, and ALSFRS-R total and bulbar scores, as well as between DDK rate and ALSFRS-R total score. Speech and pause measures in passage and timing measures in monosyllabic DDK tasks might be suitable for monitoring bulbar functional symptoms in French speakers with ALS, but more work is required to identify which measures are sensitive to the earliest stages of the disease.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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