Prevalence and Burden of Carotid and Femoral Atherosclerosis in Subjects Without Known Cardiovascular Disease in a Large Community Hospital in South-America.
Introduction: Clinical guidelines recommend measurement of arterial (carotid and femoral) plaque burden by vascular ultrasound (VUS) as a risk modifier in individuals at low or moderate risk without known atherosclerotic cardiovascular disease (ASCVD). Aim: To evaluate the prevalence of carotid and...
| Publicado en: | High Blood Pressure & Cardiovascular Prevention Vol. 31; no. 2; pp. 177 - 188 |
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| Autores principales: | , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Mar2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=176843013&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 176843013 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 11209879 1WYI jtl: High Blood Pressure & Cardiovascular Prevention issn: 11209879 maglogo: N pubinfo: dt: Mar2024 vid: 31 iid: 2 pid: 87227 pub: Springer Nature artinfo: ui: 176843013 175817469 176843013 176843013 10.1007/s40292-024-00627-3 176843013 ppf: 177 ppct: 11 formats: tig: atl: Prevalence and Burden of Carotid and Femoral Atherosclerosis in Subjects Without Known Cardiovascular Disease in a Large Community Hospital in South-America. aug: au: Botto, Fernando Obregon, Sebastian Forcada, Pedro Di Leva, Ana Fischer Sohn, Gabriela Bang, Joon-Ho Koretzky, Martin Baratta, Sergio Kotliar, Carol affil: https://ror.org/05476d639 Clinical Research Unit, Instituto Cardiovascular de Buenos Aires (ICBA), Av del Libertador 6302, Buenos Aires, Argentina sug: subj: Coronary Arteriosclerosis Epidemiology Coronary Arteriosclerosis Complications Cardiovascular Risk Factors Carotid Arteries Pathology Femoral Artery Pathology Global Burden of Disease Evaluation Hospitals, Community South America Age Factors Sex Factors Risk Assessment Human Adult Middle Age Male Female South America Prospective Studies Descriptive Statistics Comparative Studies Ultrasonography T-Tests Chi Square Test Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: Introduction: Clinical guidelines recommend measurement of arterial (carotid and femoral) plaque burden by vascular ultrasound (VUS) as a risk modifier in individuals at low or moderate risk without known atherosclerotic cardiovascular disease (ASCVD). Aim: To evaluate the prevalence of carotid and femoral plaques by age and sex, the burden of subclinical atherosclerosis (SA), and its association with classic CVRF in subjects over 30 years of age without ASCVD. Methods: We prospectively enrolled 5775 consecutive subjects referred for cardiovascular evaluation and determined the prevalence and burden of SA using 2D-VUS in carotid and femoral arteries. Results: Sixty-one percent were men with a mean age of 51.3 (SD 10.6) years. Overall, plaque prevalence was 51% in carotid arteries, 39.3% in femoral arteries, 62.4% in carotid or femoral arteries, and 37.6% in neither. The prevalence of plaques and SA burden showed an increasing trend with age, being higher in men than in women and starting before the age of 40, both in the carotid and femoral sites. There was also an increasing prevalence of plaques according to the number of CVRF, and interestingly we found a high prevalence of plaques in subjects with 0 or 1 classic CVRF. Conclusions: We observed an increased prevalence and burden of carotid or femoral SA, higher in men, beginning before the fourth decade of life and increasing with age. Despite a significant association with classic CVRF, a significant number of subjects with low CVRF were diagnosed with SA. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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