Netrin-1 Promotes M2 Type Activation and Inhibits Pyroptosis of Microglial Cells by Depressing RAC1/Nf-κB Pathway to Alleviate Inflammatory Pain.

Netrin-1 (NTN-1) plays a vital role in the progress of nervous system development and inflammatory diseases. However, the role and underlying mechanism of NTN-1 in inflammatory pain (IP) are unclear. BV2 microglia were treated with LPS to mimic the cell status under IP. Adeno-associated virus carryi...

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Bibliographic Details
Published in:Physiological Research Vol. 73; no. 2; pp. 305 - 315
Main Authors: Yanyan YIN, Yan YAN, Xia JIN, Yuanyuan FU, Ying CHEN
Format: Journal Article
Published: Institute of Physiology, Academy of Sciences of the Czech Republic Apr2024
Online Access:View this record in EBSCOhost