Classification of Neurocognition in Japanese Patients with Schizophrenia: A Cluster Analysis.
Objectives. Cognitive functions in almost all domains are lower in patients with schizophrenia than those in healthy controls, with the severity of impairment differing between domains. Treatments are being developed to improve cognitive impairment in patients with schizophrenia. However, the patter...
| Publicado en: | Perspectives in Psychiatric Care Vol. 2024; pp. 1 - 10 |
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| Autores principales: | , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
5/9/2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=177320887&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 177320887 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00315990 22L jtl: Perspectives in Psychiatric Care issn: 00315990 maglogo: Y pubinfo: dt: 5/9/2024 vid: 2024 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 177320887 177320887 177320887 10.1155/2024/3920137 177320887 ppf: 1 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Classification of Neurocognition in Japanese Patients with Schizophrenia: A Cluster Analysis. aug: au: Kurebayashi, Yusuke Otaki, Junichi affil: Faculty of Nursing, Kio University, Nara 635-0832, Japan sug: subj: Cognition Classification Cognition Disorders Therapy Schizophrenia Japanese Persons Human Cluster Analysis Cross Sectional Studies Severity of Illness Hospitals, Psychiatric Japan Memory, Short Term Evaluation One-Way Analysis of Variance Psychopathology Evaluation Spatial Perception Evaluation Processing Speed Evaluation Attention Evaluation Clinical Assessment Tools Post Hoc Analysis Length of Stay Questionnaires Signs and Symptoms Schizophrenia Drug Therapy Chi Square Test T-Tests Task Performance and Analysis Data Analysis Software Antipsychotic Agents Administration and Dosage Reaction Time Evaluation Male Female Male Female ab: Objectives. Cognitive functions in almost all domains are lower in patients with schizophrenia than those in healthy controls, with the severity of impairment differing between domains. Treatments are being developed to improve cognitive impairment in patients with schizophrenia. However, the pattern of cognitive impairment must be clarified to facilitate treatment. Therefore, this study aimed to classify the patterns of cognitive impairment in individuals and provide treatment suggestions. Methods. Patients with schizophrenia were recruited from two psychiatric hospitals in Japan. Demographic and psychopathological symptoms were assessed using the Positive and Negative Symptoms Scale for Schizophrenia and neurocognitive functions, using the CogHealth battery. The following domains were assessed: processing speed, visual attention, working memory, visual learning, and spatial attention. The scores were standardised and assigned as the same-aged average score. Hierarchical cluster analysis using Ward's method was performed based on CogHealth scores. Subsequently, one-way analysis of variance (ANOVA) and Tukey's multiple comparisons were performed to compare the variables in each cluster. Results. In total, 133 participants were classified into four clusters: Cluster 1 (n = 16), with severe cognitive impairment and psychiatric symptoms and the longest stay; Cluster 2 (n = 44), with moderate cognitive impairment and psychiatric symptoms; Cluster 3 (n = 42), with preserved cognitive function, except for spatial perception, and mild psychiatric symptoms; and Cluster 4 (n = 31), with only memory and spatial perception impairment and mild psychiatric symptoms. Implications. The clusters indicate that impairment may occur in all or selective domains. Selective domain impairments may be in spatial perception or in spatial perception and memory. Therefore, it is recommended that treatments for cognitive dysfunction are developed into four subsets considering an individual's cognitive features. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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