Prevention at home in older persons with (pre-)frailty: analysis of participants' recruitment and characteristics of the randomized controlled PromeTheus trial.
Background: The "PromeTheus" trial is evaluating a home-based, multifactorial, interdisciplinary prevention program for community-dwelling (pre-)frail older adults. These individuals often suffer from reduced participation, which can complicate the recruitment and enrollment in a clinical trial. Aim...
| Publicado en: | Aging Clinical & Experimental Research Vol. 36; no. 1; pp. 1 - 10 |
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| Autores principales: | , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
5/23/2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=177463645&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 177463645 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15940667 2WMP jtl: Aging Clinical & Experimental Research issn: 15940667 maglogo: N pubinfo: dt: 5/23/2024 vid: 36 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 177463645 177463645 177463645 10.1007/s40520-024-02775-x 177463645 ppf: 1 ppct: 9 formats: tig: atl: Prevention at home in older persons with (pre-)frailty: analysis of participants' recruitment and characteristics of the randomized controlled PromeTheus trial. aug: au: Fleiner, Tim Nerz, Corinna Denkinger, Michael Bauer, Jürgen M. Grüneberg, Christian Dams, Judith Schäufele, Martina Büchele, Gisela affil: https://ror.org/032000t02 Institute for Geriatric Research, Ulm University Medical Center, Ulm, Germany sug: subj: Research Subject Recruitment Methods Research Subjects Evaluation Community Living In Old Age Frailty Syndrome Prevention and Control Human Germany Secondary Analysis Cross Sectional Studies Male Female Aged Aged, 80 and Over Descriptive Statistics Physicians, Family Newspapers Advertising Writing Sociodemographic Factors Evaluation Functional Status Physical Mobility Evaluation Mental Status Social Behavior Phenotype Funding Source Research Subject Recruitment Economics Scales Questionnaires Aged: 65+ years Aged, 80 & over Male Female ab: Background: The "PromeTheus" trial is evaluating a home-based, multifactorial, interdisciplinary prevention program for community-dwelling (pre-)frail older adults. These individuals often suffer from reduced participation, which can complicate the recruitment and enrollment in a clinical trial. Aims: The aim of this study was to evaluate different recruitment strategies and differences in participant characteristics in relation to these strategies. Methods: This cross-sectional study used baseline data from the randomized-controlled PromeTheus trial, in which community-dwelling (pre-)frail older persons (Clinical Frailty Scale [CFS] 4–6 pt., ≥ 70 years) were recruited via general practitioners ("GP recruitment") or flyers, newspaper articles, and personalized letters ("direct recruitment"). Differences in the sociodemographic, clinical, physical, functional, mobility-related, psychological and social characteristics were analyzed in relation to the recruitment strategy. Results: A total of 385 participants (mean age = 81.2, SD 5.9 years; women: n = 283, 73.5%) were enrolled, of which 60 (16%) were recruited by GPs and 325 (84%) through direct recruitment. Participants recruited via GPs had significantly higher subjective frailty levels (CFS), were more often physically frail (Fried Frailty Phenotype), and showed lower physical capacity (Short Physical Performance Battery), participation (disability component of the short version of the Late-Life Function and Disability Instrument), and life-space mobility (Life-Space Assessment) compared to those recruited via the direct approach (p = 0.002–0.026). Costs per randomized participant were 94€ for the GP recruitment strategy and €213 for the direct recruitment strategy. Conclusion: Different strategies may be required to successfully recruit (pre-)frail home-living older adults into preventive programs. Direct recruitment strategies, in which potential participants are directly informed about the prevention program, seem to be more promising than GP recruitment but may result in enrolment of persons with less functional impairment and higher recruitment costs. Trial registration: German Clinical Trials Register, DRKS00024638. Registered on March 11, 2021. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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