Delineating Visual Habituation Profiles in Preschoolers with Neurofibromatosis Type 1 and Autism Spectrum Disorder: A Cross-Syndrome Study.

Atypical habituation to repetitive information has been commonly reported in Autism Spectrum Disorder (ASD) but it is not yet clear whether similar abnormalities are present in Neurofibromatosis Type 1 (NF1). We employed a cross-syndrome design using a novel eye tracking paradigm to measure habituat...

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Published in:Journal of Autism & Developmental Disorders Vol. 54; no. 5; pp. 1998 - 2012
Main Authors: Hocking, Darren R., Sun, Xiaoyun, Haebich, Kristina, Darke, Hayley, North, Kathryn N., Vivanti, Giacomo, Payne, Jonathan M.
Format: pictorial research tables/charts Journal Article
Published: Springer Nature May2024
Online Access:View this record in EBSCOhost
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        atl: Delineating Visual Habituation Profiles in Preschoolers with Neurofibromatosis Type 1 and Autism Spectrum Disorder: A Cross-Syndrome Study.
      aug:
        au:
          Hocking, Darren R.
          Sun, Xiaoyun
          Haebich, Kristina
          Darke, Hayley
          North, Kathryn N.
          Vivanti, Giacomo
          Payne, Jonathan M.
        affil: https://ror.org/01rxfrp27 School of Psychology and Public Health, La Trobe University, Melbourne, Australia
      sug:
        subj:
          Evoked Potentials, Visual
          Visual Perception Physiology
          Autism Spectrum Disorder Physiopathology
          Neurofibromatosis 1 Physiopathology
          Eye Movements Evaluation
          Human
          Infant
          Male
          Female
          Child
          Australia
          Cognition
          Scales
          Infant: 1-23 months
          Child: 6-12 years
          Male
          Female
      ab: Atypical habituation to repetitive information has been commonly reported in Autism Spectrum Disorder (ASD) but it is not yet clear whether similar abnormalities are present in Neurofibromatosis Type 1 (NF1). We employed a cross-syndrome design using a novel eye tracking paradigm to measure habituation in preschoolers with NF1, children with idiopathic ASD and typically developing (TD) children. Eye movements were recorded to examine fixation duration to simultaneously presented repeating and novel stimuli. Children with NF1 showed a bias for longer look durations to repeating stimuli at the expense of novel stimuli, and slower habituation in NF1 was associated with elevated ASD traits. These findings could indicate aberrant modulation of bottom-up attentional networks that interact with the emergence of ASD phenotypes.
      pubtype: Academic Journal
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        pictorial
        research
        tables/charts
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    language: English
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