Central Executive and Default Mode Networks: An Appraisal of Executive Function and Social Skill Brain-Behavior Correlates in Youth with Autism Spectrum Disorder.

Atypical connectivity patterns have been observed for individuals with autism spectrum disorders (ASD), particularly across the triple-network model. The current study investigated brain-behavior relationships in the context of social skills and executive function profiles for ASD youth. We calculat...

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Publicado en:Journal of Autism & Developmental Disorders Vol. 54; no. 5; pp. 1882 - 1897
Autores principales: Blume, Jessica, Dhanasekara, Chathurika S., Kahathuduwa, Chanaka N., Mastergeorge, Ann M.
Formato: research tables/charts Journal Article
Publicado: Springer Nature May2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2024
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10803-023-05961-4
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        atl: Central Executive and Default Mode Networks: An Appraisal of Executive Function and Social Skill Brain-Behavior Correlates in Youth with Autism Spectrum Disorder.
      aug:
        au:
          Blume, Jessica
          Dhanasekara, Chathurika S.
          Kahathuduwa, Chanaka N.
          Mastergeorge, Ann M.
        affil: Department of Human Development and Family Sciences, Texas Tech University, P.O. Box 41230, 79409-1230, Lubbock, TX, USA
      sug:
        subj:
          Autism Spectrum Disorder In Adolescence
          Functional Connectivity
          Default Mode Network
          Executive Function
          Social Skills
          Brain Physiology
          Human
          Child, Preschool
          Adolescence
          Child
          Male
          Female
          Young Adult
          Structural Equation Modeling
          Factor Analysis
          Descriptive Statistics
          Child, Preschool: 2-5 years
          Adolescent: 13-18 years
          Child: 6-12 years
          Male
          Female
      ab: Atypical connectivity patterns have been observed for individuals with autism spectrum disorders (ASD), particularly across the triple-network model. The current study investigated brain-behavior relationships in the context of social skills and executive function profiles for ASD youth. We calculated connectivity measures from diffusion tensor imaging using Bayesian estimation and probabilistic tractography. We replicated prior structural equation modeling of behavioral measures with total default mode network (DMN) connectivity to include comparisons with central executive network (CEN) connectivity and CEN-DMN connectivity. Increased within-CEN connectivity was related to metacognitive strengths. Our findings indicate behavior regulation difficulties in youth with ASD may be attributable to impaired connectivity between the CEN and DMN and social skill difficulties may be exacerbated by impaired within-DMN connectivity.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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