The association between obesity severity and food reward in adolescents with obesity: a one-stage individual participant data meta-analysis.
Background: Food reward and cue reactivity have been linked prospectively to problematic eating behaviours and excess weight gain in adults and children. However, evidence to date in support of an association between degree of adiposity and food reward is tenuous. A non-linear relationship between r...
| Publicado en: | European Journal of Nutrition Vol. 63; no. 4; pp. 1241 - 1256 |
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| Autores principales: | , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Jun2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=177559864&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 177559864 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14366207 CR0 jtl: European Journal of Nutrition issn: 14366207 maglogo: N pubinfo: dt: Jun2024 vid: 63 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 177559864 177559864 177559864 10.1007/s00394-024-03348-4 177559864 ppf: 1241 ppct: 15 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: The association between obesity severity and food reward in adolescents with obesity: a one-stage individual participant data meta-analysis. aug: au: Moore, Halim Pereira, Bruno Fillon, Alicia Miguet, Maud Masurier, Julie Beaulieu, Kristine Finlayson, Graham Thivel, David affil: EA 3533, Laboratory of the Metabolic Adaptations to Exercise Under Physiological and Pathological Conditions (AME2P), CRNH Auvergne, Clermont Auvergne University, 3 Rue de La Chebarde, 63170, Clermont-Ferrand, Aubière, France sug: subj: Obesity Severity of Illness Eating Behavior Evaluation Reward Weight Gain In Adulthood Weight Gain In Infancy and Childhood Human Meta Analysis Cues Body Composition Adolescence Obesity, Morbid Food Preferences Child Adult Anthropometry Body Mass Index Adolescent: 13-18 years Child: 6-12 years Adult: 19-44 years ab: Background: Food reward and cue reactivity have been linked prospectively to problematic eating behaviours and excess weight gain in adults and children. However, evidence to date in support of an association between degree of adiposity and food reward is tenuous. A non-linear relationship between reward sensitivity and obesity degree has been previously proposed, suggesting a peak is reached in mild obesity and decreases in more severe obesity in a quadratic fashion. Objective: To investigate and characterise in detail the relationship between obesity severity, body composition, and explicit and implicit food reward in adolescents with obesity. Methods: Data from seven clinical trials in adolescents with obesity were aggregated and analysed in an independent participant data meta-analysis. Linear and curvilinear relationships between the degree of obesity and explicit and implicit reward for sweet and high fat foods were tested in fasted and fed states with BMI-z score as a continuous and discrete predictor using clinically recognised partitions. Results: Although positive associations between obesity severity and preference for high-fat (i.e. energy dense) foods were observed when fasted, none reached significance in either analysis. Conversely, adiposity was reliably associated with lower reward for sweet, particularly when measured as implicit wanting (p = 0.012, ηp2 = 0.06), independent of metabolic state. However, this significant association was only observed in the linear model. Fat distribution was consistently associated with explicit and implicit preference for high-fat foods. Conclusions: A limited relationship was demonstrated between obesity severity and food reward in adolescents, although a lower preference for sweet could be a signal of severe obesity in a linear trend. Obesity is likely a heterogenous condition associated with multiple potential phenotypes, which metrics of body composition may help define. Clinical trial registrations: NCT02925572: https://classic.clinicaltrials.gov/ct2/show/NCT02925572. NCT03807609: https://classic.clinicaltrials.gov/ct2/show/NCT03807609. NCT03742622: https://classic.clinicaltrials.gov/ct2/show/NCT03742622. NCT03967782: https://classic.clinicaltrials.gov/ct2/show/NCT03967782. NCT03968458: https://classic.clinicaltrials.gov/ct2/show/NCT03968458. NCT04739189: https://classic.clinicaltrials.gov/ct2/show/NCT04739189. NCT05365685: https://www.clinicaltrials.gov/study/NCT05365685?tab=history. pubtype: Academic Journal doctype: meta analysis research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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