Determination of serum and gingival crevicular fluid levels of omentin in healthy and rheumatoid arthritis subjects with and without periodontitis.

Objective: The aim of this study was to assess and correlate the serum and GCF levels of omentin with the periodontal status of rheumatoid arthritis (RA) patients with and without periodontitis. Methods: Forty‐four patients were divided into four groups: group H: 11 systemically and periodontally he...

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Publicado en:Oral Diseases Vol. 30; no. 4; pp. 2645 - 2653
Autores principales: Mohit, Jyothi, Ari, Geetha, Mahendra, Jaideep, Prakash, Prashanthi, Bedi, Muskan, Dave, Pavithra H., Logaranjani, Anitha, Namasivayam, Ambalavanan
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell May2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2024
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/odi.14695
        177613974
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        atl: Determination of serum and gingival crevicular fluid levels of omentin in healthy and rheumatoid arthritis subjects with and without periodontitis.
      aug:
        au:
          Mohit, Jyothi
          Ari, Geetha
          Mahendra, Jaideep
          Prakash, Prashanthi
          Bedi, Muskan
          Dave, Pavithra H.
          Logaranjani, Anitha
          Namasivayam, Ambalavanan
        affil: Department of Periodontology, Meenakshi Ammal Dental College and Hospital, Chennai, India
      sug:
        subj:
          Serum Analysis
          Gingiva Physiology
          Exudates and Transudates Analysis
          Adipokines Analysis
          Arthritis, Rheumatoid Metabolism
          Periodontitis Diagnosis
          Human
          India
          Male
          Female
          Descriptive Statistics
          Dental Plaque
          Enzyme-Linked Immunosorbent Assay
          Proteins Blood
          Male
          Female
      ab: Objective: The aim of this study was to assess and correlate the serum and GCF levels of omentin with the periodontal status of rheumatoid arthritis (RA) patients with and without periodontitis. Methods: Forty‐four patients were divided into four groups: group H: 11 systemically and periodontally healthy subjects; group P: 11 systemically healthy subjects with periodontitis; group RA: 11 periodontally healthy subjects with rheumatoid arthritis and group RA + P: 11 rheumatoid arthritis subjects with periodontitis. Periodontal parameters (plaque index, modified gingival index, probing depth, and clinical attachment level) were recorded and serum and GCF samples were collected for the estimation of omentin using ELISA. Results: The mean value of plaque index, modified gingival index, probing depth, and clinical attachment level were significantly higher whereas serum and GCF omentin levels were found to be decreased in group IV when compared to the other groups. The significant correlation was found between the serum and GCF omentin levels with all the periodontal parameters. Conclusion: The omentin level in serum and GCF was found to be lower in RA patients with periodontitis. It is also inversely correlated with the periodontal parameters. Thus, omentin can serve as a significant diagnostic and therapeutic tool in both periodontal and rheumatoid disease.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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