Prediction of high-level fear of cancer recurrence in breast cancer survivors: An integrative approach utilizing random forest algorithm and visual nomogram.

This study is the first attempt to use a combination of regression analysis and random forest algorithm to predict the risk factors for high-level fear of cancer recurrence and develop a predictive nomogram to guide clinicians and nurses in identifying high-risk populations for high-level fear of ca...

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Published in:European Journal of Oncology Nursing Vol. 70
Main Authors: Ren, Hui, Yang, Tianye, Yin, Xin, Tong, Lingling, Shi, Jianjun, Yang, Jia, Zhu, Zhu, Li, Hongyan
Format: research Journal Article
Published: Churchill Livingstone, Inc. Jun2024
Online Access:View this record in EBSCOhost
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        14623889
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      jtl: European Journal of Oncology Nursing
      issn: 14623889
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      dt: Jun2024
      vid: 70
      pid: 1242
      pub: Churchill Livingstone, Inc.
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        177655330
        177655330
        177655330
        10.1016/j.ejon.2024.102579
        177655330
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        atl: Prediction of high-level fear of cancer recurrence in breast cancer survivors: An integrative approach utilizing random forest algorithm and visual nomogram.
      aug:
        au:
          Ren, Hui
          Yang, Tianye
          Yin, Xin
          Tong, Lingling
          Shi, Jianjun
          Yang, Jia
          Zhu, Zhu
          Li, Hongyan
        affil: Nursing Department, The First Hospital of Jilin University, Changchun, Jilin Province, China
      sug:
        subj:
          Breast Neoplasms Surgery
          Neoplasm Recurrence, Local Psychosocial Factors
          Cancer Survivors Psychosocial Factors
          Fear
          Risk Assessment
          Algorithms Utilization
          Prediction Models
          Models, Statistical
          Theory Construction
          Health Personnel Psychosocial Factors
          Oncology Nurses Psychosocial Factors
          Human
          Attitude to Illness
          Regression
          Research Subject Recruitment
          China
          Cognition
          Social Factors
          Economic Factors
          Reliability and Validity
          Psychology
          Univariate Statistics
          Multiple Regression
          Emotional Regulation
          ROC Curve
          Credibility (Research)
      ab: This study is the first attempt to use a combination of regression analysis and random forest algorithm to predict the risk factors for high-level fear of cancer recurrence and develop a predictive nomogram to guide clinicians and nurses in identifying high-risk populations for high-level fear of cancer recurrence. After receiving various recruitment strategies, a total of 781 survivors who had undergone breast cancer resection within 5 years in four Grade-A hospitals in China were included. Besides demographic and clinical characteristics, variables were also selected from the perspectives of somatic, cognitive, psychological, social and economic factors, all of which were measured using a scale with high reliability and validity. This study established univariate regression analysis and random forest model to screen for risk factors for high-level fear of cancer recurrence. Based on the results of the multi-variable regression model, a nomogram was constructed to visualize risk prediction. Fatigue, social constraints, maladaptive cognitive emotion regulation strategies, meta-cognition and age were identified as risk factors. Based on the predictive model, a nomogram was constructed, and the area under the curve was 0.949, indicating strong discrimination and calibration. The integration of two models enhances the credibility of the prediction outcomes. The nomogram effectively transformed intricate regression equations into a visual representation, enhancing the readability and accessibility of the prediction model's results. It aids clinicians and nurses in swiftly and precisely identifying high-risk individuals for high-level fear of cancer recurrence, enabling the development of timely, predictable, and personalized intervention programs for high-risk patients. • Exploring modifiable risk factors will provide great opportunities for the prevention and intervention of FCR. • Random forest can provide a simple visual method to accurately rank the importance of related factors. • Nomogram accurately converted complex regression equations into visual graphics, making the prediction model more readable.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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