Microsatellite Instability Detection in Cancer: A Multiplex qPCR Approach that Obviates the Need for Matching Normal Samples.

Background Microsatellite instability (MSI) indicates DNA mismatch repair deficiency in certain types of cancer, such as colorectal cancer. The current gold standard technique, PCR–capillary electrophoresis (CE), requires matching normal samples and specialized instrumentation. We developed VarTrace...

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Bibliographic Details

Published in:	Clinical Chemistry Vol. 70; no. 6; pp. 830 - 841
Main Authors:	Chen, Wei, Yan, Yan Helen, Young, Blake, Pinto, Alessandro, Jiang, Qi, Song, Nanjia, Yaseen, Adam, Yao, Weijie, Zhang, David Yu, Zhang, Jinny Xuemeng
Format:	Journal Article
Published:	Oxford University Press / USA Jun2024
Online Access:	View this record in EBSCOhost