Investigation of the Relationship Between Left Ventricular Hypertrophy and Endothelial Dysfunction in Patients with Primary Hypertension by ADMA and hsCRP.
Introduction: Hypertension targets many organs. This study investigates left ventricular hypertrophy (LVH), which can lead to conduction disorders, arrhythmias, and heart failure. Endothelial dysfunction (ED) was assessed using serum asymmetric dimethyl-arginine (ADMA) levels. Methods: The study inc...
| Published in: | Lokman Hekim Health Sciences Vol. 4; no. 1; pp. 44 - 50 |
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| Main Authors: | , , |
| Format: | research tables/charts Journal Article |
| Published: |
KARE Publishing
2024
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=177669090&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 177669090 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 27917835 N1MV jtl: Lokman Hekim Health Sciences issn: 27917835 maglogo: N pubinfo: dt: 2024 vid: 4 iid: 1 pid: 62027 pub: KARE Publishing artinfo: ui: 177669090 177669090 177669090 10.14744/lhhs.2024.1202 177669090 ppf: 44 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Investigation of the Relationship Between Left Ventricular Hypertrophy and Endothelial Dysfunction in Patients with Primary Hypertension by ADMA and hsCRP. aug: au: Kurt, Ömer Karaman, Murat Sağlam, Kenan affil: Department of Gastroenterology, Memorial Hospital, Ankara, Türkiye sug: subj: Hypertrophy, Left Ventricular Endothelium Physiopathology Hypertension Diagnosis Arginine Blood C-Reactive Protein Blood Human Turkiye Cross Sectional Studies Nonexperimental Studies Correlational Studies Male Female Adolescence Adult Middle Age Aged Descriptive Statistics Data Analysis Software Kruskal-Wallis Test Mann-Whitney U Test Chi Square Test Fisher's Exact Test Body Mass Index Inflammation Adolescent: 13-18 years Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Introduction: Hypertension targets many organs. This study investigates left ventricular hypertrophy (LVH), which can lead to conduction disorders, arrhythmias, and heart failure. Endothelial dysfunction (ED) was assessed using serum asymmetric dimethyl-arginine (ADMA) levels. Methods: The study included a total of 90 voluntary participants: 30 patients with hypertension and left ventricular hypertrophy, 30 hypertensive patients without hypertrophy, and 30 normotensive healthy controls. Serum ADMA levels were used to detect endothelial dysfunction. Results: The results showed that serum ADMA levels were significantly higher in the patient group compared to the control group. However, there was no significant difference in serum ADMA levels between the two subgroups of patients, with or without left ventricular hypertrophy (LVH). A correlation analysis was performed, revealing no correlation between serum ADMA levels and the left ventricular mass index (LVMI). Discussion and Conclusion: There appears to be no direct relationship between LVH and endothelial dysfunction. Furthermore, inflammatory processes seem to contribute to the development of LVH rather than endothelial dysfunction. The duration of exposure to high blood pressure and the stage of hypertension are also believed to impact this process. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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