Population pharmacokinetic analyses of methotrexate in pediatric patients: a systematic review.

Background and objectives: Methotrexate is widely utilized in the chemotherapy of malignant tumors and autoimmune diseases in the pediatric population, but dosing can be challenging. Several population pharmacokinetic models were developed to characterize factors influencing variability and improve...

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Bibliographic Details
Published in:European Journal of Clinical Pharmacology Vol. 80; no. 7; pp. 965 - 983
Main Authors: Cheng, Yu, Zhang, Yujia, Zhang, Ying, Liu, Maobai, Zhao, Limei
Format: research systematic review tables/charts Journal Article
Published: Springer Nature Jul2024
Online Access:View this record in EBSCOhost