Intersectional Stigma, Fear of Negative Evaluation, Depression, and ART Adherence Among Women Living with HIV Who Engage in Substance Use: A Latent Class Serial Mediation Analysis.
Women Living with HIV (WLHIV) who use substances face stigma related to HIV and substance use (SU). The relationship between the intersection of these stigmas and adherence to antiretroviral therapy (ART), as well as the underlying mechanisms, remains poorly understood. This study aimed to examine t...
| Publicado en: | AIDS & Behavior Vol. 28; no. 6; pp. 1882 - 1898 |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Jun2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=177742622&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 177742622 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10907165 G1T jtl: AIDS & Behavior issn: 10907165 maglogo: N pubinfo: dt: Jun2024 vid: 28 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 177742622 176030906 177742622 177742622 10.1007/s10461-024-04282-6 177742622 ppf: 1882 ppct: 16 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Intersectional Stigma, Fear of Negative Evaluation, Depression, and ART Adherence Among Women Living with HIV Who Engage in Substance Use: A Latent Class Serial Mediation Analysis. aug: au: Stringer, Kristi Lynn Norcini Pala, Andrea Cook, Robert L. Kempf, Mirjam-Colette Konkle-Parker, Deborah Wilson, Tracey E. Tien, Phyllis C. Wingood, Gina Neilands, Torsten B. Johnson, Mallory O. Logie, Carmen H. Weiser, Sheri D. Turan, Janet M. Turan, Bulent affil: https://ror.org/02n1hzn07 Department of Health and Human Performance, Community and Public Health, Middle Tennessee State University, 37132, Murfreesboro, TN, USA sug: subj: HIV-Positive Persons Psychosocial Factors HIV Infections Drug Therapy Substance Use Disorders Psychosocial Factors Substance Use Disorders Complications Antiretroviral Therapy, Highly Active Utilization Attitude to Medical Treatment Fear Depression Stigma Sex Factors Patient Compliance Women's Health Human Mediation Analysis Structural Equation Modeling Models, Statistical Female Comparative Studies Female ab: Women Living with HIV (WLHIV) who use substances face stigma related to HIV and substance use (SU). The relationship between the intersection of these stigmas and adherence to antiretroviral therapy (ART), as well as the underlying mechanisms, remains poorly understood. This study aimed to examine the association between intersectional HIV and SU stigma and ART adherence, while also exploring the potential role of depression and fear of negative evaluation (FNE) by other people in explaining this association. We analyzed data from 409 WLHIV collected between April 2016 and April 2017, Using Multidimensional Latent Class Item Response Theory analysis. We identified five subgroups (i.e., latent classes [C]) of WLHIV with different combinations of experienced SU and HIV stigma levels: (C1) low HIV and SU stigma; (C2) moderate SU stigma; (C3) higher HIV and lower SU stigma; (C4) moderate HIV and high SU stigma; and (C5) high HIV and moderate SU stigma. Medication adherence differed significantly among these classes. Women in the class with moderate HIV and high SU stigma had lower adherence than other classes. A serial mediation analysis suggested that FNE and depression symptoms are mechanisms that contribute to explaining the differences in ART adherence among WLHIV who experience different combinations of intersectional HIV and SU stigma. We suggest that FNE is a key intervention target to attenuate the effect of intersectional stigma on depression symptoms and ART adherence, and ultimately improve health outcomes among WLHIV. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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