Long-term outcome of multilayer flow modulator in aortic aneurysms.

This retrospective study investigated the efficacy of endovascular treatment with multilayer flow modulators (MFMs) for treating aortic aneurysms in high-risk patients unsuitable for conventional treatments. Conducted from 2011 to 2019 at a single center, this retrospective observational study inclu...

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Publicado en:Radiology & Oncology Vol. 58; no. 2; pp. 206 - 214
Autores principales: Pintaric, Karlo, Boltezar, Lucka, Umek, Nejc, Kuhelj, Dimitrij
Formato: diagnostic images research tables/charts Journal Article
Publicado: Paradigm Publishing Services Jun2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2024
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      pub: Paradigm Publishing Services
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        10.2478/raon-2024-0021
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        atl: Long-term outcome of multilayer flow modulator in aortic aneurysms.
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        au:
          Pintaric, Karlo
          Boltezar, Lucka
          Umek, Nejc
          Kuhelj, Dimitrij
        affil: Clinical Institute of Radiology, University Medical Center Ljubljana, Slovenia
      sug:
        subj:
          Patient Safety
          Endovascular Aneurysm Repair
          Blood Vessel Prosthesis Equipment and Supplies
          Aortic Aneurysm Surgery
          Treatment Outcomes
          Human
          Male
          Female
          Middle Age
          Aged
          Aged, 80 and Over
          Nonexperimental Studies
          Retrospective Design
          Record Review
          Computed Tomography Angiography
          Aorta, Abdominal Anatomy and Histology
          Hemodynamics
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: This retrospective study investigated the efficacy of endovascular treatment with multilayer flow modulators (MFMs) for treating aortic aneurysms in high-risk patients unsuitable for conventional treatments. Conducted from 2011 to 2019 at a single center, this retrospective observational study included 17 patients who underwent endovascular treatment with MFMs. These patients were selected based on their unsuitability for traditional surgical or endovascular procedures. The study involved meticulous pre-procedural planning, precise implantation of MFMs, and follow-up using CT angiography. The primary focus was on volumetric and flow volume changes in aneurysms, along with traditional diameter measurements. Moreover, the technical success and post-procedural complications were also registered. The technical success rate was 100%, and 30-day procedural complication rate was 17.6%. Post-treatment assessments revealed that 11 out of 17 patients showed a decrease in flow volume within the aneurysm sac, indicative of a favorable hemodynamic response. The median decrease in flow volume was 12 ml, with a median relative decrease of 8%. However, there was no consistent reduction in aneurysm size; most aneurysms demonstrated a median increase in volume for 46 ml and median increase in diameter for 18 mm. While MFMs offer a potential alternative for high-risk aortic aneurysm patients, their effectiveness in preventing aneurysm expansion is limited. The results suggest that MFMs can provide a stable hemodynamic environment but do not reliably reduce aneurysm size. This underscores the need for ongoing vigilance and long-term monitoring in patients treated with this technology.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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