The Validation Of COVID-19 Information In The Pharmacoepidemiological Research Database of Spain's Public Health System Data by Vaccination Status.

Purpose To validate COVID-19 information records in The Pharmacoepidemiological Research Database for Public Health System (BIFAP) of Spain. Methods The recorded COVID-19 cases in primary care or positive test registries (gold-standard) were identified among vaccinated patients against COVID-19 infe...

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Published in:Perspectives in Health Information Management Vol. 21; no. 1; pp. 95 - 110
Main Authors: Astasio, Oliver, Castillo-Cano, Belén, Sánchez Delgado, Beatriz, Riefolo, Fabio, Gini, Rosa, Martín-Merino, Elisa
Format: research tables/charts Journal Article
Published: American Health Information Management Association Winter/Spring2024
Online Access:View this record in EBSCOhost
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        atl: The Validation Of COVID-19 Information In The Pharmacoepidemiological Research Database of Spain's Public Health System Data by Vaccination Status.
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          Astasio, Oliver
          Castillo-Cano, Belén
          Sánchez Delgado, Beatriz
          Riefolo, Fabio
          Gini, Rosa
          Martín-Merino, Elisa
      sug:
        subj:
          COVID-19 Vaccines
          Health Information
          Vaccination Status Evaluation
          Databases, Health Spain
          Public Health
          Validation Studies
          COVID-19 Diagnosis
          Human
          Male
          Female
          Adolescence
          Adult
          Middle Age
          Aged
          Spain
          Descriptive Statistics
          Sensitivity and Specificity
          Predictive Value of Tests
          Measurement Error
          Electronic Health Records
          Vaccine Efficacy
          Patient Safety
          Algorithms
          Health Information Systems
          Data Analysis Software
          Funding Source
          Adolescent: 13-18 years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Purpose To validate COVID-19 information records in The Pharmacoepidemiological Research Database for Public Health System (BIFAP) of Spain. Methods The recorded COVID-19 cases in primary care or positive test registries (gold-standard) were identified among vaccinated patients against COVID-19 infection and their matched unvaccinated controls, between December 2020 and October 2021. The sensitivity, specificity, positive (PPV) and negative (NPV) predictive values were estimated for primary care records. Results Among 21,702 patients with positive tests and 20,866 with recorded COVID-19 diagnoses, the sensitivity, specificity, PPV and NPV were, respectively, 79.98 percent, 99.95 percent, 80.24 percent, and 99.94 percent among vaccinated, and 78.67 percent, 99.96 percent, 84.51 percent and 99.94 percent among controls. Conclusions Primary care COVID-19 diagnosis recorded in BIFAP showed that sensitivity was similar and PPV was slightly lower among vaccinated than unvaccinated controls. Among the elderly, COVID-19 diagnosis was less recorded. These findings permit the design of informed algorithms for performing COVID-19-related studies.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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