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The effectiveness of turmeric supplementation in reducing low-density lipoprotein cholesterol in adults.

This review reports the findings of seven systematic reviews and meta-analyses evaluating the effectiveness of turmeric/curcumin as a dietary supplement in reducing LDL-cholesterol (LDL-C). PubMed was searched for publications between January 1st, 2018 and August 23th, 2023, reporting on the anticho...

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Published in:Revista Mexicana de Endocrinología, Metabolismo y Nutrición Vol. 11; no. 2; pp. 60 - 74
Main Author: HESSON, JAMES
Format: meta analysis research systematic review tables/charts Journal Article
Published: Publicidad Permanyer SLU apr-jun2024
Online Access:View this record in EBSCOhost
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      dt: apr-jun2024
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      pub: Publicidad Permanyer SLU
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        atl: The effectiveness of turmeric supplementation in reducing low-density lipoprotein cholesterol in adults.
      aug:
        au: HESSON, JAMES
        affil: Department of Healthcare and Behavioral Sciences, Medical Writing Certificate Program, University of California, San Diego Extended Studies, La Jolla, California, USA
      sug:
        subj:
          Turmeric Pharmacodynamics
          Dietary Supplementation
          Lipoproteins, LDL Cholesterol Drug Effects
          Curcumin Pharmacodynamics
          Human
          Systematic Review
          Meta Analysis
          Adult
          PubMed
          Antioxidants Therapeutic Use
          Antiinflammatory Agents Therapeutic Use
          Descriptive Statistics
          Functional Food
          Adult: 19-44 years
      ab:
        This review reports the findings of seven systematic reviews and meta-analyses evaluating the effectiveness of turmeric/curcumin as a dietary supplement in reducing LDL-cholesterol (LDL-C). PubMed was searched for publications between January 1st, 2018 and August 23th, 2023, reporting on the anticholesteremic effects of turmeric. Turmeric demonstrates antioxidant, anti-inflammatory, and anticholesteremic activity. A dosage of 850 mg/d for 10 weeks reduced LDL-C in adults over 50 years old at risk for cardiovascular disease. One study reported curcumin reduced LDL-C by a mean of 39.83 mg/dL. Yet, other reports conflicting findings on the effectiveness of turmeric supplementation, likely due to high-heterogeneity in between-study endpoints, dosage, duration, and participant characteristics. Turmeric has potential as a safe, effective, inexpensive, lipid-lowering functional food. Future studies must clarify the degree to which turmeric improves lipid indices, its mechanism of action, and the most effective form, dose, route, and duration in reducing LDL-C.
        Esta revisión informa sobre los hallazgos de siete revisiones sistemáticas y metanálisis que evalúan la efectividad de la cúrcuma como suplemento dietético para reducir el colesterol-LDL (LDLC). Se buscaron en PubMed publicaciones entre el primero de enero de 2018 y el 23 de agosto de 2023 que informaran sobre los efectos anticolesterémicos de la cúrcuma. La cúrcuma demuestra ser antioxidante, posee actividad antiinflamatoria y anticolesterémica. Una dosis de 850 mg/día redujo el C-LDL en adultos mayores de 50 años con riesgo de enfermedad cardiovascular. Un estudio informó que la curcumina redujo el C-LDL en una media de 39,83 mg/dL. Sin embargo, otros informan hallazgos contradictorios sobre la cúrcuma, probablemente debido a la alta heterogeneidad en los criterios de valoración, la dosis, la duración y las características de los participantes entre los estudios. La cúrcuma tiene potencial como alimento funcional reductor de lípidos, seguro, eficaz y económico. Los estudios futuros deben aclarar el grado en que la cúrcuma mejora los índices de lípidos, su mecanismo de acción y la forma, dosis, vía y duración más efectivas para reducir el C-LDL.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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