Performance of the 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology Classification Criteria for antineutrophil cytoplasmic antibody-associated vasculitis in previously diagnosed adult patients from Türkiye.

Objectives: This study aimed to evaluate the applicability of the new 2022 American College of Rheumatology (ACR)/European Alliance of Associations for Rheumatology (EULAR) criteria in Turkish adult patients previously diagnosed with antineutrophil cytoplasmic antibody-associated vasculitis (AAV). P...

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Publicado en:Archives of Rheumatology Vol. 39; no. 2; pp. 194 - 203
Autores principales: Yilmaz, Sedat, Kucuk, Hamit, Ozgunen, Merve Sungur, Kardas, Riza Can, Tecer, Duygu, Vasi, Ibrahim, Cinar, Muhammet, Ozturk, Mehmet Akif
Formato: research tables/charts Journal Article
Publicado: Aves Yayincilik A.S. Jun2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2024
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      pub: Aves Yayincilik A.S.
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        10.46497/ArchRheumatol.2024.10268
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        atl: Performance of the 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology Classification Criteria for antineutrophil cytoplasmic antibody-associated vasculitis in previously diagnosed adult patients from Türkiye.
      aug:
        au:
          Yilmaz, Sedat
          Kucuk, Hamit
          Ozgunen, Merve Sungur
          Kardas, Riza Can
          Tecer, Duygu
          Vasi, Ibrahim
          Cinar, Muhammet
          Ozturk, Mehmet Akif
        affil: Department of Internal Medicine, Division of Rheumatology, University of Health Sciences, Gülhane Training and Research Hospital, Ankara, Türkiye
      sug:
        subj:
          Vasculitis Diagnosis
          Antibodies, Antineutrophil Cytoplasmic
          Professional Organizations Europe
          Organizations, Nonprofit
          Predictive Value of Tests
          Sensitivity and Specificity
          Human
          Europe
          Male
          Female
          Adolescence
          Adult
          Middle Age
          Aged
          Aged, 80 and Over
          Rheumatologists
          Granulomatosis with Polyangiitis Classification
          Churg-Strauss Syndrome Classification
          Retrospective Design
          Cross Sectional Studies
          Microscopic Polyangiitis Classification
          Algorithms
          kappa Statistic
          Adolescent: 13-18 years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Objectives: This study aimed to evaluate the applicability of the new 2022 American College of Rheumatology (ACR)/European Alliance of Associations for Rheumatology (EULAR) criteria in Turkish adult patients previously diagnosed with antineutrophil cytoplasmic antibody-associated vasculitis (AAV). Patients and methods: One hundred sixty-four patients (96 males, 68 females; mean age: 49.6±14.4 years; range, 18 to 87 years) diagnosed with AAV by experienced rheumatologists between July 2016 and May 2022 were included in this retrospective cross-sectional study and reclassified based on the 1990 ACR criteria, the European Medicines Agency (EMEA) algorithm, and the 2022 ACR/EULAR criteria. For external validation, 83 patients (48 males, 35 females; mean age: 47.3±17.5 years; range, 19 to 81 years) diagnosed with immunoglobulin (Ig)A vasculitis were included. Results: One hundred twenty-six (76.8%) patients had granulomatosis with polyangiitis (GPA), 13 (7.9%) patients had eosinophilic granulomatosis with polyangiitis (EGPA), and 25 (15.2%) patients had microscopic polyangiitis (MPA). According to the criteria, the number of unclassified patients was nine (5.5%) for both the 2022 ACR/EULAR AAV classification criteria and the EMEA algorithm. The new criteria had an almost perfect agreement with the clinician's diagnosis (Cohen's kappa coefficient [k]=0.858 for GPA, k=0.820 for EGPA, and k=0.847 for MPA). The kappa statistics for agreement of 2022 ACR/EULAR classification criteria with the EMEA algorithm were found 0.794 for GPA, 0.820 for EGPA, and 0.700 for MPA. None of the 83 patients diagnosed with IgA vasculitis could be classified as GPA, EGPA, or MPA using the new ACR/EULAR AAV classification criteria. Conclusion: The 2022 ACR/EULAR classification criteria for AAV showed substantial or perfect agreement with the clinical diagnosis and the EMEA algorithm.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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