Bisphenol derivatives in cord blood and association between thyroid hormones and potential exposure sources.

Endocrine-disrupting environmental chemicals are a public health concern, particularly fetal exposure to Bisphenol derivatives. This study aimed to assess fetal exposure to Bisphenol derivatives (BPA, BPF, and BPS) by measuring their levels in cord blood and investigating their association with plas...

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Detalles Bibliográficos
Publicado en:International Journal of Environmental Health Research Vol. 34; no. 8; pp. 3036 - 3046
Autores principales: Buke Sahin, Merve, Cagan, Murat, Yirun, Anıl, Balcı Ozyurt, Aylin, Erdemli Kose, Selinay Basak, Iyigun, Irem, Celik, Melda, Ozyuncu, Ozgur, Erkekoglu, Pınar, Yavuz, Cavit Isik
Formato: research tables/charts Journal Article
Publicado: Taylor & Francis Ltd Aug2024
Acceso en línea:Ver este registro en EBSCOhost
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Sumario:Endocrine-disrupting environmental chemicals are a public health concern, particularly fetal exposure to Bisphenol derivatives. This study aimed to assess fetal exposure to Bisphenol derivatives (BPA, BPF, and BPS) by measuring their levels in cord blood and investigating their association with plastic material used in daily life as well as cord blood TSH and free L-thyroxine (fT4) levels. In this descriptive study, a questionnaire with a face-to-face interview was administered before birth, and cord blood samples were taken immediately after delivery. The mean levels of BPA, BPF, TSH, and fT4 were measured as 10.69 ± 2.39 ng/ml, 3.80 ± 0.58 ng/ml; 2.36 ± 0.23 µIU/ml, and 14.18 ± 0.53 pg/ml, respectively, in a total of 104 cord blood samples. All BPS levels remained below the detection limit. Linear regression analysis revealed a positive association between birth weight and cord blood BPA concentration (β = 0.26; p = 0.02). Further research on maternal exposure during the fetal and neonatal period is critical for public health.