Automated prediction of isthmus areas in scar‐related atrial tachycardias using artificial intelligence.

Introduction: Ablation of scar‐related reentrant atrial tachycardia (SRRAT) involves identification and ablation of a critical isthmus. A graph convolutional network (GCN) is a machine learning structure that is well‐suited to analyze the irregularly‐structured data obtained in mapping procedures an...

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Published in:Journal of Cardiovascular Electrophysiology Vol. 35; no. 7; pp. 1401 - 1412
Main Authors: Saluja, Deepak, Huang, Ziyi, Majumder, Jonah, Zeldin, Lawrence, Yarmohammadi, Hirad, Biviano, Angelo, Wan, Elaine Y., Ciaccio, Edward J., Hendon, Christine P., Garan, Hasan
Format: pictorial research tables/charts Journal Article
Published: Wiley-Blackwell Jul2024
Online Access:View this record in EBSCOhost
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      dt: Jul2024
      vid: 35
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/jce.16299
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        atl: Automated prediction of isthmus areas in scar‐related atrial tachycardias using artificial intelligence.
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          Saluja, Deepak
          Huang, Ziyi
          Majumder, Jonah
          Zeldin, Lawrence
          Yarmohammadi, Hirad
          Biviano, Angelo
          Wan, Elaine Y.
          Ciaccio, Edward J.
          Hendon, Christine P.
          Garan, Hasan
        affil: Division of Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York New York,, USA
      sug:
        subj:
          Artificial Intelligence Utilization
          Tachycardia, Atrial Diagnosis
          Tachycardia, Atrial Surgery
          Tachycardia, Atrial Physiopathology
          Cicatrix Physiopathology
          Cicatrix Diagnosis
          Automation
          Predictive Value of Tests
          Catheter Ablation Methods
          Action Potentials
          Machine Learning
          Treatment Outcomes
          Human
          Male
          Female
          Middle Age
          Aged
          United States
          Heart Function Tests
          Heart Rate
          Signal Processing, Computer Assisted
          Funding Source
          Descriptive Statistics
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Introduction: Ablation of scar‐related reentrant atrial tachycardia (SRRAT) involves identification and ablation of a critical isthmus. A graph convolutional network (GCN) is a machine learning structure that is well‐suited to analyze the irregularly‐structured data obtained in mapping procedures and may be used to identify potential isthmuses. Methods: Electroanatomic maps from 29 SRRATs were collected, and custom electrogram features assessing key tissue and wavefront properties were calculated for each point. Isthmuses were labeled off‐line. Training data was used to determine the optimal GCN parameters and train the final model. Putative isthmus points were predicted in the training and test populations and grouped into proposed isthmus areas based on density and distance thresholds. The primary outcome was the distance between the centroids of the true and closest proposed isthmus areas. Results: A total of 193 821 points were collected. Thirty isthmuses were detected in 29 tachycardias among 25 patients (median age 65.0, 5 women). The median (IQR) distance between true and the closest proposed isthmus area centroids was 8.2 (3.5, 14.4) mm in the training and 7.3 (2.8, 16.1) mm in the test group. The mean overlap in areas, measured by the Dice coefficient, was 11.5 ± 3.2% in the training group and 13.9 ± 4.6% in the test group. Conclusion: A GCN can be trained to identify isthmus areas in SRRATs and may help identify critical ablation targets.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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