Contribution of the cadaveric recirculation system in the anatomical study of lymphatic drainage of the ovary: applications in the management of ovarian cancer.

Purpose: The present knowledge about lymphatic drainage of the ovary is based on carcinological studies, but it has only rarely been studied under physiological conditions. However, it is one of the preferential routes of dissemination in ovarian cancer, and understanding it is therefore vital for o...

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Published in:Surgical & Radiologic Anatomy Vol. 46; no. 8; pp. 1155 - 1165
Main Authors: Murris, Floriane, Weyl, Ariane, Ouldamer, Lobna, Lorenzini, Jérôme, Delvallee, Julie, Martinez, Alejandra, Ferron, Gwenael, Chollet, Charlotte, De Barros, Amaury, Chantalat, Elodie
Format: Journal Article
Published: Springer Nature Aug2024
Online Access:View this record in EBSCOhost
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      dt: Aug2024
      vid: 46
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00276-024-03406-w
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        atl: Contribution of the cadaveric recirculation system in the anatomical study of lymphatic drainage of the ovary: applications in the management of ovarian cancer.
      aug:
        au:
          Murris, Floriane
          Weyl, Ariane
          Ouldamer, Lobna
          Lorenzini, Jérôme
          Delvallee, Julie
          Martinez, Alejandra
          Ferron, Gwenael
          Chollet, Charlotte
          De Barros, Amaury
          Chantalat, Elodie
        affil: Département de chirurgie gynécologique, Chu Bretonneau Tours, 37000, Tours, France
      sug:
      ab: Purpose: The present knowledge about lymphatic drainage of the ovary is based on carcinological studies, but it has only rarely been studied under physiological conditions. However, it is one of the preferential routes of dissemination in ovarian cancer, and understanding it is therefore vital for optimal carcinological management.Our purpose was to evaluate the feasibility of an innovative technique to study the lymphatic drainage territories of the ovary using a recirculation module on the cadaveric model. Methods: We injected patent blue into the cortex of twenty "revascularised" cadaver ovaries with the Simlife recirculation model. We observed the migration of the dye live and described the drainage territories of each ovary. Results: We observed a staining of the lymphatic vessels and migration of the dye in all the subjects, systematically ipsilateral to the injected ovary. We identified a staining of the lumbo-aortic territory in 65% of cases, with a preferential lateral-caval involvement (60%) for the right ovary and lateral-aortic territory (40%) for the left ovary. A common iliac involvement was observed in only 10% of cases. In 57% of cases, the staining of the lumbo-aortic territory was associated with a staining of the suspensory ligament. The pelvic territory was involved in 50% of cases, with an external iliac staining in 25% of cases and internal in 20%. Conclusion: Our study provides for a better understanding of lymphatic drainage of the ovary using a new detection method, and allows the possibility of improving the teaching for operators with a realistic model. Continuation of this work could lead to considering more targeted and thus less morbid lymph node sampling for lymph node staging in early-stage ovarian cancer.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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