Use of the experience sampling method in adolescents with Duchenne muscular dystrophy: a feasibility study.

Experience sampling methods (ESM) using mobile health (mHealth) technology with a smartphone application are increasingly used in clinical practice and research. Still, recommendations are limited in young people, and adaptations may be necessary. Patients with Duchenne muscular dystrophy (DMD) are...

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Publicado en:European Child & Adolescent Psychiatry Vol. 33; no. 7; pp. 2281 - 2291
Autores principales: Lionarons, Judith M., Delespaul, Philippe A. E. G., Hellebrekers, Danique M. J., Broen, Martinus P. G., Klinkenberg, Sylvia, Faber, Catharina G., Hendriksen, Jos G. M., Vles, Johan S. H.
Formato: pictorial research tables/charts Journal Article
Publicado: Springer Nature Jul2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2024
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00787-023-02317-2
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        atl: Use of the experience sampling method in adolescents with Duchenne muscular dystrophy: a feasibility study.
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          Lionarons, Judith M.
          Delespaul, Philippe A. E. G.
          Hellebrekers, Danique M. J.
          Broen, Martinus P. G.
          Klinkenberg, Sylvia
          Faber, Catharina G.
          Hendriksen, Jos G. M.
          Vles, Johan S. H.
        affil: https://ror.org/02jz4aj89 School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands
      sug:
        subj:
          Muscular Dystrophy, Duchenne Drug Therapy
          Adrenal Cortex Hormones Adverse Effects
          Mobile Applications Utilization
          Severity of Illness
          Telehealth
          Cognition Disorders Risk Factors
          Behavioral Symptoms Risk Factors
          Risk Assessment
          Human
          Pilot Studies
          Sampling Methods
          Muscular Dystrophy, Duchenne Symptoms
          Program Implementation
          Child
          Adolescence
          Descriptive Statistics
          Patient Compliance
          Child: 6-12 years
          Adolescent: 13-18 years
      ab: Experience sampling methods (ESM) using mobile health (mHealth) technology with a smartphone application are increasingly used in clinical practice and research. Still, recommendations are limited in young people, and adaptations may be necessary. Patients with Duchenne muscular dystrophy (DMD) are chronically treated with steroids from a young age. However, the impact of intermittent treatment schedules on fluctuations in somatic, cognitive and behavioural symptoms is poorly investigated. Existing studies are often cross-sectional and occur in controlled clinical settings, which do not provide sufficiently detailed insights into possible correlations. ESM might alleviate these problems. ESM innovates data collection with a smartphone application, which repeatedly assesses specific symptoms and contextual factors at random moments in daily life. We aimed to evaluate its feasibility in adolescents with DMD. In three (without/with/without steroids) 4-day periods of ESM, that were nested in 10/10 or 11/9 day on/off-medication periods, we evaluated its user-friendliness and compliance, and explored its ability to objectify fluctuations in somatic, cognitive and behavioural symptom severity and their relationship with contextual factors in seven DMD patients (age range 12–18 years) using intermittent corticosteroid treatment (dosage range 0.3–0.6 mg/kg/day). Patients reported that ESM was convenient and user-friendly. We were able to capture extensive intra-individual symptom fluctuations during intermittent corticosteroid treatment that were not revealed by routine clinical assessment. Implementing ESM to evaluate symptom fluctuation patterns in relation to treatment effects shows promise in adolescents with DMD. Optimization in further research is needed.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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