Neoadjuvant Nivolumab Plus Chemotherapy Followed By Response-Adaptive Therapy for HPV+ Oropharyngeal Cancer: OPTIMA II Phase 2 Open-Label Nonrandomized Controlled Trial.

Key Points: Question: Is neoadjuvant nivolumab with chemotherapy followed by response-adapted locoregional therapy effective and well tolerated in patients with human papillomavirus−positive oropharyngeal carcinoma (HPV+ OPC)? Findings: This phase 2 nonrandomized controlled trial of 73 patients with...

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Publicado en:JAMA Oncology Vol. 10; no. 7; pp. 923 - 932
Autores principales: Rosenberg, Ari J., Agrawal, Nishant, Juloori, Aditya, Cursio, John, Gooi, Zhen, Blair, Elizabeth, Chin, Jeffrey, Ginat, Daniel, Pasternak-Wise, Olga, Hasina, Rifat, Starus, Anna, Jones, Frederick S., Izumchenko, Evgeny, MacCracken, Ellen, Wolk, Rachelle, Cipriani, Nicole, Lingen, Mark W., Pearson, Alexander T., Seiwert, Tanguy Y., Haraf, Daniel J.
Formato: research tables/charts Journal Article
Publicado: American Medical Association Jul2024
Acceso en línea:Ver este registro en EBSCOhost