The effect of dietary approaches to stop hypertension (DASH) diet on fatty liver and cardiovascular risk factors in subjects with metabolic syndrome: a randomized controlled trial.
Background: Metabolic syndrome (MetS) as a multifactorial disorder is associated with non-communicable diseases. The dietary approaches to stop hypertension (DASH) diet is a healthy dietary pattern. We investigated the effect of the DASH diet on fatty liver and cardiovascular risk factors in subject...
| Publicado en: | BMC Endocrine Disorders Vol. 24; no. 1; pp. 1 - 11 |
|---|---|
| Autores principales: | , , |
| Formato: | research tables/charts randomized controlled trial Journal Article |
| Publicado: |
BioMed Central
7/25/2024
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=178621311&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 178621311 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14726823 1CHL jtl: BMC Endocrine Disorders issn: 14726823 maglogo: N pubinfo: dt: 7/25/2024 vid: 24 iid: 1 pid: 24147 pub: BioMed Central artinfo: ui: 178621311 178621311 178621311 10.1186/s12902-024-01661-x 178621311 ppf: 1 ppct: 10 formats: tig: atl: The effect of dietary approaches to stop hypertension (DASH) diet on fatty liver and cardiovascular risk factors in subjects with metabolic syndrome: a randomized controlled trial. aug: au: Sangouni, Abbas Ali Hosseinzadeh, Mahdieh Parastouei, Karim affil: https://ror.org/01ysgtb61 Health Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran sug: subj: Metabolic Syndrome X Complications Hypertension Diet Therapy DASH Diet Fatty Liver Risk Factors Cardiovascular Risk Factors Risk Assessment Fatty Liver Prevention and Control Cardiovascular Diseases Prevention and Control Treatment Outcomes Human Male Female Adult Middle Age Funding Source Data Analysis Software Paired T-Tests Chi Square Test Univariate Statistics Analysis of Covariance Food Intake Dietary Patterns Waist Circumference Body Weight Body Mass Index Triglycerides Cholesterol Randomized Controlled Trials Random Assignment Lipoproteins, LDL Lipoproteins, HDL Cholesterol Anthropometry Disease Management Descriptive Statistics Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: Background: Metabolic syndrome (MetS) as a multifactorial disorder is associated with non-communicable diseases. The dietary approaches to stop hypertension (DASH) diet is a healthy dietary pattern. We investigated the effect of the DASH diet on fatty liver and cardiovascular risk factors in subjects with MetS. Methods: 60 Subjects with MetS were assigned into the intervention group (DASH diet) or the control group (a healthy diet). Fatty liver index (FLI), hepatic steatosis index (HSI), waist circumference (WC), weight, body mass index (BMI), triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-c) and high-density lipoprotein cholesterol (HDL-c) were evaluated at the beginning and after intervention. Equations of fatty liver indices such as FLI and HSI are based on liver enzymes, anthropometric variables, sex and having diabetes. Results: 30 subjects in the intervention group and 29 subjects in the control group completed the study. We found a significant reduction in the intervention group compared to the control group in FLI (-13.06 ± 10.03 vs. -2.90 ± 6.82;P < 0.001), HSI (-2.72 ± 2.59 vs. -0.81 ± 3.80;P = 0.02), WC (-6.02 ± 4.24 vs. -2.24 ± 4.28;P = 0.001), weight (-3.39 ± 2.53 vs. -1.51 ± 2.72;P = 0.008), BMI (-1.25 ± 0.93 vs. -0.56 ± 1.01;P = 0.008), DBP (-5.16 ± 3.92 vs. -1.50 ± 7.04;P = 0.01), SBP (-6.97 ± 8.21 vs. -1.36 ± 6.83;P = 0.006), TG (-18.50 ± 14.32 vs. 0.60 ± 23.81;P < 0.001), TC (-16.10 ± 17.94 vs. -5.07 ± 23.62;P = 0.04) and LDL-c (-13.50 ± 9.58 vs. -4.90 ± 18.28;P = 0.02). These results remained significant after adjusting for confounding factors, except for TC (P = 0.25). Conclusions: The DASH diet was more effective than the control diet in managing fatty liver and cardiovascular risk factors. Trial registration: The trial was registered on 21 October 2022 at Iranian Registry of Clinical Trials (IRCT20180201038585N12, URL: https://irct.behdasht.gov.ir/trial/66161). pubtype: Academic Journal doctype: research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|