Machine Learning Predicts Unplanned Care Escalations for Post-Anesthesia Care Unit Patients during the Perioperative Period: A Single-Center Retrospective Study.

Background: Despite low mortality for elective procedures in the United States and developed countries, some patients have unexpected care escalations (UCE) following post-anesthesia care unit (PACU) discharge. Studies indicate patient risk factors for UCE, but determining which factors are most imp...

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Publicado en:Journal of Medical Systems Vol. 48; no. 1; pp. 1 - 12
Autores principales: Barker, Andrew B., Melvin, Ryan L., Godwin, Ryan C., Benz, David, Wagener, Brant M.
Formato: research tables/charts Journal Article
Publicado: Springer Nature 7/23/2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 7/23/2024
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10916-024-02085-9
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        atl: Machine Learning Predicts Unplanned Care Escalations for Post-Anesthesia Care Unit Patients during the Perioperative Period: A Single-Center Retrospective Study.
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          Barker, Andrew B.
          Melvin, Ryan L.
          Godwin, Ryan C.
          Benz, David
          Wagener, Brant M.
        affil: https://ror.org/008s83205 Division of Critical Care Medicine, Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, 901 19th Street South, PBMR 302, 35294, Birmingham, AL, United States of America
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        subj:
          Post Anesthesia Care Units
          Surgical Patients
          Clinical Deterioration Risk Factors
          Postoperative Complications Risk Factors
          Risk Assessment
          Preoperative Period
          Machine Learning
          Human
          Funding Source
          Male
          Female
          Adult
          Middle Age
          Retrospective Design
          Record Review
          Vital Signs
          Emergencies
          Anesthesia
          Time Factors
          Oxygen Saturation
          Systolic Pressure
          Heart Rate
          Respiratory Rate
          Regression
          Data Analysis Software
          T-Tests
          Chi Square Test
          Fisher's Exact Test
          ROC Curve
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Background: Despite low mortality for elective procedures in the United States and developed countries, some patients have unexpected care escalations (UCE) following post-anesthesia care unit (PACU) discharge. Studies indicate patient risk factors for UCE, but determining which factors are most important is unclear. Machine learning (ML) can predict clinical events. We hypothesized that ML could predict patient UCE after PACU discharge in surgical patients and identify specific risk factors. Methods: We conducted a single center, retrospective analysis of all patients undergoing non-cardiac surgery (elective and emergent). We collected data from pre-operative visits, intra-operative records, PACU admissions, and the rate of UCE. We trained a ML model with this data and tested the model on an independent data set to determine its efficacy. Finally, we evaluated the individual patient and clinical factors most likely to predict UCE risk. Results: Our study revealed that ML could predict UCE risk which was approximately 5% in both the training and testing groups. We were able to identify patient risk factors such as patient vital signs, emergent procedure, ASA Status, and non-surgical anesthesia time as significant variable. We plotted Shapley values for significant variables for each patient to help determine which of these variables had the greatest effect on UCE risk. Of note, the UCE risk factors identified frequently by ML were in alignment with anesthesiologist clinical practice and the current literature. Conclusions: We used ML to analyze data from a single-center, retrospective cohort of non-cardiac surgical patients, some of whom had an UCE. ML assigned risk prediction for patients to have UCE and determined perioperative factors associated with increased risk. We advocate to use ML to augment anesthesiologist clinical decision-making, help decide proper disposition from the PACU, and ensure the safest possible care of our patients.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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