Head-to-head comparison of three different US-based quantitative parameters for hepatic steatosis assessment: a prospective study.
Purpose: To evaluate the diagnostic performance of attenuation coefficient (AC), hepato-renal index (HRI) and controlled attenuation parameter (CAP) in quantitative assessment of hepatic steatosis by employing histopathology as reference standard. Methods: Participants with suspected metabolic-assoc...
| Publicado en: | Abdominal Radiology Vol. 49; no. 7; pp. 2262 - 2272 |
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| Autores principales: | , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Jul2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=178678131&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 178678131 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 2366004X JT14 jtl: Abdominal Radiology issn: 2366004X maglogo: N pubinfo: dt: Jul2024 vid: 49 iid: 7 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 178678131 177176710 10.1007/s00261-024-04347-z 178678131 ppf: 2262 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Head-to-head comparison of three different US-based quantitative parameters for hepatic steatosis assessment: a prospective study. aug: au: Zhou, Yan Nie, Mengjin Zhou, Hongyu Mao, Feng Zhao, Lin Ding, Jianmin Jing, Xiang affil: https://ror.org/00911j719 Department of Ultrasound, Tianjin Third Central Hospital, Hedong District, No. 83 Jintang Road, 300170, Tianjin, China sug: ab: Purpose: To evaluate the diagnostic performance of attenuation coefficient (AC), hepato-renal index (HRI) and controlled attenuation parameter (CAP) in quantitative assessment of hepatic steatosis by employing histopathology as reference standard. Methods: Participants with suspected metabolic-associated fatty liver disease (MAFLD) who underwent US-based parameter examinations and liver biopsy were prospectively recruited. The distributions of US parameters across different grades of steatosis were calculated, and diagnostic performance was determined based on the areas under the receiver operating characteristic curve (AUC). Results: A total of 73 participants were included, with hepatic steatosis grades S0, S1, S2, and S3 distributed as follows: 13, 20, 27, and 13 respectively. The correlation coefficients for CAP, AC, and HRI ranged from 0.67 to 0.74. AC and HRI showed a strong correlation with steatosis grade. The AUC for CAP and AC in diagnosing steatosis ≥ S1 were significantly higher at 0.99 and 0.98 compared to HRI's value. For diagnosing steatosis ≥ S2, the AUC of CAP (AUC: 0.85) was lower than that of AC (AUC: 0.94), and HRI (AUC: 0.94). Similarly for diagnosing steatosis S3, the AUC of CAP (AUC: 0.68) was lower than that of AC (AUC: 0.88), and HRI (AUC: 0.88). Conclusion: The AC and HRI values increased with the progression of hepatic steatosis grade, while CAP increased from S0 to S2 but not from S2 to S3. For mild steatosis diagnosis, CAP and AC showed superior diagnostic performance compared to HRI, while AC and HRI were more advantageous in differentiating moderate and severe steatosis. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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