Association between paravertebral muscle radiological parameter alterations and non-alcoholic fatty liver disease.
Purpose: To assess changes in laboratory indices, paravertebral muscle (PVM) fat infiltration and multi b-value DWI parameters and their potential correlation with NAFLD. Methods: This retrospective analysis included 178 patients with histopathologically confirmed NAFLD, incluiding 76 with non-alcoh...
| Publicado en: | Abdominal Radiology Vol. 49; no. 7; pp. 2250 - 2262 |
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| Autores principales: | , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Jul2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=178678135&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 178678135 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 2366004X JT14 jtl: Abdominal Radiology issn: 2366004X maglogo: N pubinfo: dt: Jul2024 vid: 49 iid: 7 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 178678135 177475903 10.1007/s00261-024-04352-2 178678135 ppf: 2250 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Association between paravertebral muscle radiological parameter alterations and non-alcoholic fatty liver disease. aug: au: Lin, Lulu Chen, Mengjiao Huang, Xiaoyan Song, Jiawen Ye, Xinjian Liu, Kun Han, Lu Yan, Zhihan Zheng, Minghua Liu, Xiaozheng affil: https://ror.org/0156rhd17 Department of Radiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China sug: ab: Purpose: To assess changes in laboratory indices, paravertebral muscle (PVM) fat infiltration and multi b-value DWI parameters and their potential correlation with NAFLD. Methods: This retrospective analysis included 178 patients with histopathologically confirmed NAFLD, incluiding 76 with non-alcoholic steatohepatitis (NASH). Differences in PVM fat infiltration ratio (FIR), DWI parameters, and laboratory indices were compared between two groups. The correlation between FIR and NAFLD activity score (NAS) was also analysed. Binary logistic regression was used to identify the independent risk factors for NASH. The clinical utility of PVM fat infiltration, DWI parameters, and laboratory indices for diagnosing NASH in patients with NAFLD was evaluated using receiver operating characteristic (ROC) curves. Results: The FIRs at the L2 and L3 levels were significantly higher in the with NASH group than those in the without NASH group. The heterogeneity index (α) and perfusion fraction (f) values at the L3 level of PVM were lower in the with NASH group. Moreover, the FIR at the L3 level was positively correlated with NAS. FIR at the L3 level was an independent risk factor for NASH along with alanine aminotransferase level. The area under the ROC curve (AUC) using L3 level PVM radiological parameters and laboratory indices for diagnosing NASH in patients with NAFLD was significantly higher than that using the degree of PVM fat infiltration, DWI parameters, or laboratory indices alone. Conclusions: Radiological parameters of the PVM were correlated with NAFLD. An integrated curve combining PVM radiological parameters may help distinguish NASH from NAFLD, thereby offering novel insights into the diagnosis of NASH. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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