Predicting T-Cell Lymphoma in Children From 18F-FDG PET-CT Imaging With Multiple Machine Learning Models.
This study aimed to examine the feasibility of utilizing radiomics models derived from 18F-FDG PET/CT imaging to screen for T-cell lymphoma in children with lymphoma. All patients had undergone 18F-FDG PET/CT scans. Lesions were extracted from PET/CT and randomly divided into training and validation...
| Publicado en: | Journal of Digital Imaging Vol. 37; no. 3; pp. 952 - 965 |
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| Autores principales: | , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Springer Nature
Jun2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=178678168&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 178678168 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 08971889 DOQ jtl: Journal of Digital Imaging issn: 08971889 maglogo: N pubinfo: dt: Jun2024 vid: 37 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 178678168 178678168 178678168 10.1007/s10278-024-01007-y 178678168 ppf: 952 ppct: 13 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Predicting T-Cell Lymphoma in Children From 18F-FDG PET-CT Imaging With Multiple Machine Learning Models. aug: au: Yang, Taiyu Liu, Danyan Zhang, Zexu Sa, Ri Guan, Feng affil: https://ror.org/034haf133 Department of Nuclear Medicine, The First Hospital of Jilin University, 1# Xinmin St, 130021, Changchun, China sug: subj: Lymphoma, T-Cell Radiography Fludeoxyglucose F 18 Diagnostic Use Cancer Screening Radiographic Image Interpretation, Computer-Assisted Machine Learning Prediction Models Radiomics Human Child Comparative Studies Validation Studies Funding Source Tomography, X-Ray Computed Random Assignment Logistic Regression Support Vector Machine Neural Networks (Computer) Descriptive Statistics Childhood Neoplasms Radiography Child: 6-12 years ab: This study aimed to examine the feasibility of utilizing radiomics models derived from 18F-FDG PET/CT imaging to screen for T-cell lymphoma in children with lymphoma. All patients had undergone 18F-FDG PET/CT scans. Lesions were extracted from PET/CT and randomly divided into training and validation sets. Two different types of models were constructed as follows: features that are extracted from standardized uptake values (SUV)-associated parameters, and CT images were used to build SUV/CT-based model. Features that are derived from PET and CT images were used to build PET/CT-based model. Logistic regression (LR), linear support vector machine, support vector machine with the radial basis function kernel, neural networks, and adaptive boosting were performed as classifiers in each model. In the training sets, 77 patients, and 247 lesions were selected for building the models. In the validation sets, PET/CT-based model demonstrated better performance than that of SUV/CT-based model in the prediction of T-cell lymphoma. LR showed highest accuracy with 0.779 [0.697, 0.860], area under the receiver operating characteristic curve (AUC) with 0.863 [0.762, 0.963], and preferable goodness-of-fit in PET/CT-based model at the patient level. LR also showed best performance with accuracy of 0.838 [0.741, 0.936], AUC of 0.907 [0.839, 0.976], and preferable goodness-of-fit in PET/CT-based model at the lesion level. 18F-FDG PET/CT-based radiomics models with different machine learning classifiers were able to screen T-cell lymphoma in children with high accuracy, AUC, and preferable goodness-of-fit, providing incremental value compared with SUV-associated features. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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