Basal Cell Carcinoma Diagnosis with Fusion of Deep Learning and Telangiectasia Features.

In recent years, deep learning (DL) has been used extensively and successfully to diagnose different cancers in dermoscopic images. However, most approaches lack clinical inputs supported by dermatologists that could aid in higher accuracy and explainability. To dermatologists, the presence of telan...

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Publicado en:Journal of Digital Imaging Vol. 37; no. 3; pp. 1137 - 1151
Autores principales: Maurya, Akanksha, Stanley, R. Joe, Aradhyula, Hemanth Y., Lama, Norsang, Nambisan, Anand K., Patel, Gehana, Saeed, Daniyal, Swinfard, Samantha, Smith, Colin, Jagannathan, Sadhika, Hagerty, Jason R., Stoecker, William V.
Formato: diagnostic images pictorial research tables/charts Journal Article
Publicado: Springer Nature Jun2024
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-024-00969-3
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        atl: Basal Cell Carcinoma Diagnosis with Fusion of Deep Learning and Telangiectasia Features.
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          Maurya, Akanksha
          Stanley, R. Joe
          Aradhyula, Hemanth Y.
          Lama, Norsang
          Nambisan, Anand K.
          Patel, Gehana
          Saeed, Daniyal
          Swinfard, Samantha
          Smith, Colin
          Jagannathan, Sadhika
          Hagerty, Jason R.
          Stoecker, William V.
        affil: https://ror.org/00scwqd12 Missouri University of Science &Technology, 65209, Rolla, MO, USA
      sug:
        subj:
          Carcinoma, Basal Cell Diagnosis
          Carcinoma, Basal Cell Pathology
          Deep Learning
          Telangiectasis Pathology
          Human
          Sensitivity and Specificity
          Dermoscopy
          Image Interpretation, Computer Assisted
          Skin Neoplasms Pathology
          Carcinoma, Basal Cell Classification
          Descriptive Statistics
      ab: In recent years, deep learning (DL) has been used extensively and successfully to diagnose different cancers in dermoscopic images. However, most approaches lack clinical inputs supported by dermatologists that could aid in higher accuracy and explainability. To dermatologists, the presence of telangiectasia, or narrow blood vessels that typically appear serpiginous or arborizing, is a critical indicator of basal cell carcinoma (BCC). Exploiting the feature information present in telangiectasia through a combination of DL-based techniques could create a pathway for both, improving DL results as well as aiding dermatologists in BCC diagnosis. This study demonstrates a novel "fusion" technique for BCC vs non-BCC classification using ensemble learning on a combination of (a) handcrafted features from semantically segmented telangiectasia (U-Net-based) and (b) deep learning features generated from whole lesion images (EfficientNet-B5-based). This fusion method achieves a binary classification accuracy of 97.2%, with a 1.3% improvement over the corresponding DL-only model, on a holdout test set of 395 images. An increase of 3.7% in sensitivity, 1.5% in specificity, and 1.5% in precision along with an AUC of 0.99 was also achieved. Metric improvements were demonstrated in three stages: (1) the addition of handcrafted telangiectasia features to deep learning features, (2) including areas near telangiectasia (surround areas), (3) discarding the noisy lower-importance features through feature importance. Another novel approach to feature finding with weak annotations through the examination of the surrounding areas of telangiectasia is offered in this study. The experimental results show state-of-the-art accuracy and precision in the diagnosis of BCC, compared to three benchmark techniques. Further exploration of deep learning techniques for individual dermoscopy feature detection is warranted.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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