Impact of CYP2C19, CYP2C9, CYP3A4, and FMO3 Genetic Polymorphisms and Sex on the Pharmacokinetics of Voriconazole after Single and Multiple Doses in Healthy Chinese Subjects.

Voriconazole is the first‐line treatment for invasive aspergillosis. Its pharmacokinetics exhibit considerable inter‐ and intra‐individual variability. The purpose of this study was to investigate the effects of CYP2C19, CYP2C9, CYP3A4, and FMO3 genetic polymorphisms and sex on the pharmacokinetics...

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Bibliographic Details

Published in:	Journal of Clinical Pharmacology Vol. 64; no. 8; pp. 1030 - 1044
Main Authors:	Liu, Shuaibing, Yao, Xia, Tao, Jun, Zhao, Shiyu, Sun, Suke, Wang, Suyun, Tian, Xin
Format:	research tables/charts Journal Article
Published:	Wiley-Blackwell Aug2024
Online Access:	View this record in EBSCOhost