Cover Image
QR Code

Endoscopic Grading and Sampling of Gastric Precancerous Lesions: A Comprehensive Literature Review.

Gastric cancer remains a disease with an ominous prognosis, while early gastric cancer has a good-to-excellent prognosis, with 5-year survival rates of up to 92.6% after successful endoscopic resection. In this context, the accurate identification of patients with established gastric precancerous le...

Full description

Published in:Current Oncology Vol. 31; no. 7; pp. 3923 - 3939
Main Authors: Tziatzios, Georgios, Ziogas, Dimitrios Ι., Gkolfakis, Paraskevas, Papadopoulos, Vasilios, Papaefthymiou, Apostolis, Mathou, Nikoletta, Giannakopoulos, Athanasios, Gerasimatos, Gerasimos, Paraskeva, Konstantina D., Triantafyllou, Konstantinos
Format: Journal Article
Published: MDPI Jul2024
Online Access:View this record in EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=178699738&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 178699738
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        11980052
        5EKK
      jtl: Current Oncology
      issn: 11980052
      maglogo: N
    pubinfo:
      dt: Jul2024
      vid: 31
      iid: 7
      pid: 97109
      pub: MDPI
    artinfo:
      ui:
        178699738
        10.3390/curroncol31070290
        178699738
      ppf: 3923
      ppct: 16
      formats:
        fmt:
          – @attributes:
              type: T
          – @attributes:
              type: P
      tig:
        atl: Endoscopic Grading and Sampling of Gastric Precancerous Lesions: A Comprehensive Literature Review.
      aug:
        au:
          Tziatzios, Georgios
          Ziogas, Dimitrios Ι.
          Gkolfakis, Paraskevas
          Papadopoulos, Vasilios
          Papaefthymiou, Apostolis
          Mathou, Nikoletta
          Giannakopoulos, Athanasios
          Gerasimatos, Gerasimos
          Paraskeva, Konstantina D.
          Triantafyllou, Konstantinos
        affil: Department of Gastroenterology, General Hospital of Nea Ionia "Konstantopoulio-Patision", 3-5, Theodorou Konstantopoulou, 14233 Athens, Greece
      sug:
      ab: Gastric cancer remains a disease with an ominous prognosis, while early gastric cancer has a good-to-excellent prognosis, with 5-year survival rates of up to 92.6% after successful endoscopic resection. In this context, the accurate identification of patients with established gastric precancerous lesions, namely chronic atrophic gastritis and intestinal metaplasia, is the first step in a stepwise approach to minimize cancer risk. Although current guidelines advocate for the execution of random biopsies to stage the extent and severity of gastritis/intestinal metaplasia, modern biopsy protocols are still imperfect as they have limited reproducibility and are susceptible to sampling error. The advent of novel imaging-enhancing modalities, i.e., high-definition with virtual chromoendoscopy (CE), has revolutionized the inspection of gastric mucosa, leading to an endoscopy-based staging strategy for the management of these premalignant changes in the stomach. Nowadays, the incorporation of CE-targeted biopsies in everyday clinical practice offers not only the robust detection of premalignant lesions but also an improvement in quality, by reducing missed diagnoses along with mean biopsies and, thus, the procedural costs and the environmental footprint. In this review, we summarize the recent evidence regarding the endoscopic grading and sampling of gastric precancerous lesions.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N