Studying the Effect of Magnetron Copper Deposition on the Surface Topography of Biodegradable Antibacterial Coating.
Background: The surface properties of the materials used significantly influence the success and longevity of medical implants. Increasing surface roughness promotes osteoblast activity and osseointegration, while biodegradable materials such as copper have shown potential for antimicrobial applicat...
| Publicado en: | Avicenna Journal of Medical Biotechnology Vol. 16; no. 3; pp. 174 - 180 |
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| Autores principales: | , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Avicenna Research Institute
Jul-Sep2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=178703093&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 178703093 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 20082835 ATX9 jtl: Avicenna Journal of Medical Biotechnology issn: 20082835 maglogo: N pubinfo: dt: Jul-Sep2024 vid: 16 iid: 3 pid: 56911 pub: Avicenna Research Institute artinfo: ui: 178703093 178703093 178703093 10.18502/ajmb.v16i3.15743 178703093 ppf: 174 ppct: 6 formats: tig: atl: Studying the Effect of Magnetron Copper Deposition on the Surface Topography of Biodegradable Antibacterial Coating. aug: au: Bauyrzhan, Maratuly Azamatov, Bagdat Nurlanovich Jes, Alexey Vladimirovich affil: East Kazakhstan Technical University, Competence center, Smart Engineering, Oskemen, Kazakhstan sug: subj: Prostheses and Implants Copper Therapeutic Use Biodegradable Materials Therapeutic Use Antibiotics Therapeutic Use Surface Properties Evaluation Human Funding Source Osteoblasts Osseointegration Microscopy, Electron, Scanning Image Processing, Computer Assisted Ions Simulations Biofilms Staphylococcus Aureus Prosthesis-Related Infections Prevention and Control Drug Efficacy ab: Background: The surface properties of the materials used significantly influence the success and longevity of medical implants. Increasing surface roughness promotes osteoblast activity and osseointegration, while biodegradable materials such as copper have shown potential for antimicrobial applications. However, the effect of coating parameters on surface topography is not well investigated. Methods: Sputtering of copper was performed using EPOS-PVD-440 system (Zelenograd, Russia). The samples were examined by Scanning Electron Microscopy (SEM) with subsequent image processing in Mountains software (Digital Surf). Antibacterial efficacy was evaluated against Staphylococcus aureus by measuring the zone of inhibition. Additionally, copper ion release was monitored over time to assess its correlation with changes in surface topography. Results: Higher sputtering currents increased surface roughness and particle size, with a significant release of copper ions within the first 24 hr of immersion. Samples sputtered at higher currents exhibited coarser grain structures. The release of copper ions in the simulated biological environment led to further changes in surface topography, high-lighting the critical influence of sputtering parameters on coating properties. Conclusion: Optimizing magnetron copper deposition parameters enhances the surface topography and antibacterial effectiveness of biodegradable coatings on implants. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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