Neurobiology and Treatment of Posttraumatic Stress Disorder.
The recent worldwide surge of warfare and hostilities exposes increasingly large numbers of individuals to traumatic events, placing them at risk of developing posttraumatic stress disorder (PTSD) and challenging both clinicians and service delivery systems. This overview summarizes and updates the...
| Publicado en: | American Journal of Psychiatry Vol. 181; no. 8; pp. 705 - 720 |
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| Autores principales: | , , |
| Formato: | Artículo |
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American Psychiatric Publishing, Inc.
Aug2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=178737548&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 178737548 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 0002953X API jtl: American Journal of Psychiatry issn: 0002953X maglogo: N pubinfo: dt: Aug2024 vid: 181 iid: 8 pid: 37323 pub: American Psychiatric Publishing, Inc. artinfo: ui: 178737548 10.1176/appi.ajp.20240536 ppf: 705 ppct: 15 formats: tig: atl: Neurobiology and Treatment of Posttraumatic Stress Disorder. aug: au: Shalev, Arieh Cho, Dayeon Marmar, Charles R. affil: Department of Psychiatry, NYU Grossman School of Medicine, New York. su: Post-traumatic stress disorder Evidence-based psychotherapy Biocomplexity Molecular biology Neural circuitry sug: subj: Post-traumatic stress disorder Evidence-based psychotherapy Biocomplexity Molecular biology Neural circuitry keyword: Genetics/Genomics Molecular Biology Neurobiology Posttraumatic Stress Disorder (PTSD) Genetics/Genomics Molecular Biology Neurobiology Posttraumatic Stress Disorder (PTSD) ab: The recent worldwide surge of warfare and hostilities exposes increasingly large numbers of individuals to traumatic events, placing them at risk of developing posttraumatic stress disorder (PTSD) and challenging both clinicians and service delivery systems. This overview summarizes and updates the core knowledge of the genetic, molecular, and neural circuit features of the neurobiology of PTSD and advances in evidence-based psychotherapy, pharmacotherapy, neuromodulation, and digital treatments. While the complexity of the neurobiology and the biological and clinical heterogeneity of PTSD have challenged clinicians and researchers, there is an emerging consensus concerning the underlying mechanisms and approaches to diagnosis, treatment, and prevention of PTSD. This update addresses PTSD diagnosis, prevalence, course, risk factors, neurobiological mechanisms, current standard of care, and innovations in next-generation treatment and prevention strategies. It provides a comprehensive summary and concludes with areas of research for integrating advances in the neurobiology of the disorder with novel treatment and prevention targets. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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