Associations Between Autism Spectrum Quotient and Integration of Visual Stimuli in 9-year-old Children: Preliminary Evidence of Sex Differences.

Purpose: The dorsal stream vulnerability hypothesis posits that the dorsal stream, responsible for visual motion and visuo-motor processing, may be particularly vulnerable during neurodevelopment. Consistent with this, autism spectrum disorder (ASD) has been associated with deficits in global motion...

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Publicado en:Journal of Autism & Developmental Disorders Vol. 54; no. 8; pp. 2987 - 2998
Autores principales: Silva, Andrew E., Harding, Jane E., Chakraborty, Arijit, Dai, Darren W., Gamble, Greg D., McKinlay, Christopher J.D., Nivins, Samson, Shah, Rajesh, Thompson, Benjamin
Formato: research tables/charts Journal Article
Publicado: Springer Nature Aug2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2024
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        10.1007/s10803-023-06035-1
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        atl: Associations Between Autism Spectrum Quotient and Integration of Visual Stimuli in 9-year-old Children: Preliminary Evidence of Sex Differences.
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          Silva, Andrew E.
          Harding, Jane E.
          Chakraborty, Arijit
          Dai, Darren W.
          Gamble, Greg D.
          McKinlay, Christopher J.D.
          Nivins, Samson
          Shah, Rajesh
          Thompson, Benjamin
        affil: https://ror.org/01aff2v68 School of Optometry and Vision Science, University of Waterloo, Waterloo, ON, Canada
      sug:
        subj:
          Autism Spectrum Disorder In Infancy and Childhood
          Visual Perception Physiology
          Human
          Male
          Female
          Child
          Linear Regression
          Sex Factors
          Descriptive Statistics
          Mental Disorders Diagnosed in Childhood
          Questionnaires
          Child: 6-12 years
          Male
          Female
      ab: Purpose: The dorsal stream vulnerability hypothesis posits that the dorsal stream, responsible for visual motion and visuo-motor processing, may be particularly vulnerable during neurodevelopment. Consistent with this, autism spectrum disorder (ASD) has been associated with deficits in global motion integration, though deficits in ventral stream tasks, such as form identification, have also been reported. In the current study, we examined whether a similar pattern of results is found in a cohort of 381 children born with neurodevelopmental risk factors and exhibiting a wide spectrum of caregiver-reported autistic traits. Methods: We examined the associations between global motion perception, global form perception, fine motor function, visual-motor integration, and autistic traits (autism spectrum quotient, AQ) using linear regression, accounting for possible interactions with sex and other factors relevant to neurodevelopment. Results: All assessments of dorsal stream function were significantly associated with AQ such that worse performance predicted higher AQ scores. We also observed a significant sex interaction, with worse global form perception associated with higher AQ in boys (n = 202) but not girls (n = 179). Conclusion: We found widespread associations between dorsal stream functions and autistic traits. These associations were observed in a large group of children with a range of AQ scores, demonstrating a range of visual function across the full spectrum of autistic traits. In addition, ventral function was associated with AQ in boys but not girls. Sex differences in the associations between visual processing and neurodevelopment should be considered in the designs of future studies.
      pubtype: Academic Journal
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      ougenre: Article
    language: English
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