Frailty on the island of Ireland: evidence from the NICOLA and TILDA studies.

Background Aimed to compare the prevalence, characteristics, and associated mortality risk of frailty in Northern Ireland (NI) and the Republic of Ireland (ROI). Methods Secondary analysis of the first wave of two nationally representative cohorts, the Northern Ireland Cohort for the Longitudinal St...

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Publicado en:European Journal of Public Health Vol. 34; no. 4; pp. 710 - 717
Autores principales: McKelvie, Mische-Jasmine, Cruise, Sharon, Ward, Mark, Romero-Ortuno, Roman, Kee, Frank, Kenny, Rose Anne, O'Reilly, Dermot, O'Halloran, Aisling M
Formato: research tables/charts Journal Article
Publicado: Oxford University Press / USA Aug2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2024
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      pub: Oxford University Press / USA
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        atl: Frailty on the island of Ireland: evidence from the NICOLA and TILDA studies.
      aug:
        au:
          McKelvie, Mische-Jasmine
          Cruise, Sharon
          Ward, Mark
          Romero-Ortuno, Roman
          Kee, Frank
          Kenny, Rose Anne
          O'Reilly, Dermot
          O'Halloran, Aisling M
        affil: Centre for Public Health, Queen's University of Belfast , Belfast, UK
      sug:
        subj:
          Frailty Syndrome Epidemiology
          Frailty Syndrome Mortality
          Mortality Risk Factors
          Frail Elderly Statistics and Numerical Data
          Geriatric Assessment
          Aging
          Human
          Ireland
          Male
          Female
          Middle Age
          Aged
          Aged, 80 and Over
          Prospective Studies
          Secondary Analysis
          Descriptive Statistics
          Northern Ireland
          Confidence Intervals
          Prevalence
          Comparative Studies
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Background Aimed to compare the prevalence, characteristics, and associated mortality risk of frailty in Northern Ireland (NI) and the Republic of Ireland (ROI). Methods Secondary analysis of the first wave of two nationally representative cohorts, the Northern Ireland Cohort for the Longitudinal Study of Ageing or NICOLA study (N  = 8504) and the Irish Longitudinal Study on Ageing or TILDA study (N  = 8504). Frailty was assessed using a harmonized accumulation deficits frailty index (FI) containing 30 items. FI scores classified individuals as non-frail (<0.10), pre-frail (0.10–0.24) and frail (≥0.25). Linkage to respective administrative data sources provided mortality information with a follow-up time of 8 years. Results The prevalence of frailty was considerably higher in NI compared with the ROI (29.0% compared with 15.0%), though pre-frailty was slightly lower (35.8% and 37.3%, respectively). Age, female sex, and lower socio-economic status were consistently associated with a higher likelihood of both pre-frailty and frailty. In the pooled analysis, both frailty and pre-frailty were higher in NI (RR = 2.68, 95% CIs 2.45, 2.94 and RR = 1.30, 95% CIs 1.21, 1.40, respectively). Frailty was associated with an increased mortality risk in both cohorts, even after full adjustment for all other characteristics, being marginally higher in TILDA than in NICOLA (HR = 2.43, 95% CIs 2.03, 2.91 vs. HR = 2.31, 95% CIs 1.90, 2.79). Conclusions Frailty is a major public health concern for both jurisdictions. Further research and monitoring are required to elucidate why there is a higher prevalence in NI and to identify factors in early life that may be driving these differences.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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