Is the Caudate, Putamen, and Globus Pallidus the Delusional Disorder's Trio? A Texture Analysis Study.

Background: The neurobiological basis of delusional disorder is less explored through neuroimaging techniques than in other psychotic disorders. This study aims to provide information about the neural origins of delusional disorder (DD) by examining the neuroanatomical features of some basal nuclei...

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Publicado en:Actas Espanolas de Psiquiatria Vol. 52; no. 3; pp. 256 - 268
Autores principales: Baykara, Murat, Baykara, Sema
Formato: Artículo
Publicado: Maria Lopez-Ibor 2024
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Is the Caudate, Putamen, and Globus Pallidus the Delusional Disorder's Trio? A Texture Analysis Study.
      aug:
        au:
          Baykara, Murat
          Baykara, Sema
        affil:
          Department of Radiology, Haydarpasa Numune Training and Research Hospital, 34668 Istanbul, Türkiye
          Department of Psychiatry, Erenkoy Psychiatry and Neurology Training and Research Hospital, 34736 Istanbul, Türkiye
      su:
        Texture analysis (Image processing)
        Delusions
        Magnetic resonance imaging
        Globus pallidus
        Basal ganglia
      sug:
        subj:
          Texture analysis (Image processing)
          Delusions
          Magnetic resonance imaging
          Globus pallidus
          Basal ganglia
      keyword:
        caudate nucleus
        computer-assisted image processing
        delusional disorder
        globus pallidus
        magnetic resonance imaging
        putamen
      ab: Background: The neurobiological basis of delusional disorder is less explored through neuroimaging techniques than in other psychotic disorders. This study aims to provide information about the neural origins of delusional disorder (DD) by examining the neuroanatomical features of some basal nuclei with magnetic resonance imaging (MRI) texture analysis. Materials and Methods: Twenty DD patients and 20 healthy individuals were included in the study. Globus pallidus, putamen, and caudate nuclei were selected individually with a region of interest (ROI) on the axial MRI images. The entire texture analysis algorithm applied to all selected ROIs was done with an in-house software. Nuclei on both sides were taken as separate samples. Results: There were no significant differences between groups in terms of age and gender. The average "mean, median and maximum" values of all three nuclei were decreased in DD patients. The small putamen area and the differences detected in different tissue parameters for all three nuclei in delusional disorder patients indicate that they differ in delusional disorder from normal controls (p < 0.05). Conclusion: The differences detected in the texture parameters for all three nuclei indicate that there is something different in the DD from in the normal controls. Neuroimaging studies with larger samples and different techniques in the future may shed light on the etiology of delusional disorder.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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      custom: Copyright of Actas Espanolas de Psiquiatria is the property of Maria Lopez-Ibor and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use.
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