Is EEG Entropy a Useful Measure for Alzheimer's Disease?
Background: The number of individuals diagnosed with Alzheimer's disease (AD) has increased, and it is estimated to continue rising in the coming years. The diagnosis of this disease is challenging due to variations in onset and course, its diverse clinical manifestations, and the indications for me...
| Published in: | Actas Espanolas de Psiquiatria Vol. 52; no. 3; pp. 347 - 365 |
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| Main Authors: | , , , , , , , |
| Format: | Article |
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Maria Lopez-Ibor
2024
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=lth&AN=178873642&site=ehost-live header: @attributes: shortDbName: lth uiTerm: 178873642 longDbName: MedicLatina uiTag: AN controlInfo: bkinfo: jinfo: jid: 11399287 IVZ jtl: Actas Espanolas de Psiquiatria issn: 11399287 maglogo: N pubinfo: dt: 2024 vid: 52 iid: 3 pid: 80014 pub: Maria Lopez-Ibor artinfo: ui: 178873642 10.62641/aep.v52i3.1632 ppf: 347 ppct: 18 formats: fmt: @attributes: type: P size: 2MB tig: atl: Is EEG Entropy a Useful Measure for Alzheimer's Disease? aug: au: Zúñiga, Manuel A. Acero-González, Ángela Restrepo-Castro, Juan C. Uribe-Laverde, Miguel Ángel Botero-Rosas, Daniel A. Ferreras, Borja I. Molina-Borda, María C. Villa-Reyes, María Paula affil: Facultad de Medicina, Universidad Nacional de Colombia,111321 Bogotá, Colombia Facultad de Medicina, Universidad de La Sabana, 250001 Chía, Cundinamarca, Colombia Facultad de Psicología, Universidad de La Sabana, 250001 Chía, Cundinamarca, Colombia Facultad de Ingeniería, Universidad de La Sabana, 250001 Chía, Cundinamarca, Colombia su: Alzheimer's disease Science databases Symptoms Cognition disorders Entropy sug: subj: Alzheimer's disease Science databases Symptoms Cognition disorders Entropy keyword: biomarkers dementia electroencephalography entropy ab: Background: The number of individuals diagnosed with Alzheimer's disease (AD) has increased, and it is estimated to continue rising in the coming years. The diagnosis of this disease is challenging due to variations in onset and course, its diverse clinical manifestations, and the indications for measuring deposit biomarkers. Hence, there is a need to develop more precise and less invasive diagnostic tools. Multiple studies have considered using electroencephalography (EEG) entropy measures as an indicator of the onset and course of AD. Entropy is deemed suitable as a potential indicator based on the discovery that variations in its complexity can be associated with specific pathologies such as AD. Methodology: Following PRISMA guidelines, a literature search was conducted in 4 scientific databases, and 40 articles were analyzed after discarding and filtering. Results: There is a diversity in entropy measures; however, Sample Entropy (SampEn) and Multiscale Entropy (MSE) are the most widely used (21/40). In general, it is found that when comparing patients with controls, patients exhibit lower entropy (20/40) in various areas. Findings of correlation with the level of cognitive decline are less consistent, and with neuropsychiatric symptoms (2/40) or treatment response less explored (2/40), although most studies show lower entropy with greater severity. Machine learning-based studies show good discrimination capacity. Conclusions: There is significant difficulty in comparing multiple studies due to their heterogeneity; however, changes in Multiscale Entropy (MSE) scales or a decrease in entropy levels are considered useful for determining the presence of AD and measuring its severity. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: Y custom: Copyright of Actas Espanolas de Psiquiatria is the property of Maria Lopez-Ibor and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. item: Actas Espanolas de Psiquiatria holder: Maria Lopez-Ibor dt: @attributes: year: 2024 holdings: @attributes: islocal: N |
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