A Dose-Response Study to Examine Paraxanthine's Impact on Energy Expenditure, Hunger, Appetite, and Lipolysis.
This study investigated if paraxanthine (PX) impacts energy expenditure, lipolysis and perceptual responses. In a randomized, double-blind, placebo-controlled, crossover fashion, 21 adults (13 M, 8 F; 26.0 ± 6.4 years, 174.9 ± 11.5 cm, 81.0 ± 15.7 kg body mass, 26.3 ± 3.4 kg/m2) consumed a placebo (...
| Publicado en: | Journal of Dietary Supplements Vol. 21; no. 5; pp. 608 - 633 |
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| Autores principales: | , , , , , , , , , |
| Formato: | equations & formulas research tables/charts randomized controlled trial Journal Article |
| Publicado: |
Taylor & Francis Ltd
2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=178880786&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 178880786 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 19390211 2Y62 jtl: Journal of Dietary Supplements issn: 19390211 maglogo: N pubinfo: dt: 2024 vid: 21 iid: 5 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 178880786 177239081 178880786 178880786 10.1080/19390211.2024.2351222 178880786 ppf: 608 ppct: 25 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: A Dose-Response Study to Examine Paraxanthine's Impact on Energy Expenditure, Hunger, Appetite, and Lipolysis. aug: au: Gross, Kristen N. Allen, Leah E. Hagele, Anthony M. Krieger, Joesi M. Sutton, Paige J. Duncan, Esther Mumford, Petey W. Jäger, Ralf Purpura, Martin Kerksick, Chad M. affil: Exercise and Performance Nutrition Laboratory, Kinesiology Department, College of Science, Technology, and Health, Lindenwood University, St. Charles, MO, USA sug: subj: Dose-Response Relationship Caffeine Analysis Energy Metabolism Hunger Appetite Adipose Tissue Human Funding Source Texas Male Female Adult Randomized Controlled Trials Double-Blind Studies Crossover Design Descriptive Statistics Analysis of Variance Heart Rate Evaluation Comparative Studies Fatty Acids Glycerin Metabolites Adult: 19-44 years Male Female ab: This study investigated if paraxanthine (PX) impacts energy expenditure, lipolysis and perceptual responses. In a randomized, double-blind, placebo-controlled, crossover fashion, 21 adults (13 M, 8 F; 26.0 ± 6.4 years, 174.9 ± 11.5 cm, 81.0 ± 15.7 kg body mass, 26.3 ± 3.4 kg/m2) consumed a placebo (PLA), 100 mg (PX100), 200 mg (PX200), and 300 mg of PX (PX300, enfinity®, Ingenious Ingredients, L.P. Lewisville, TX, USA). Venous blood was collected 0, 30, 60, 90, 120 and 180 min (min) after ingestion and analyzed for glycerol and free fatty acids. Resting hemodynamics, metabolic rate and perceptual indicators of hunger, appetite and anxiety were evaluated. Mixed factorial analysis of variance were used to evaluate changes time within and between groups. Heart rate decreased in PX100 compared to PLA 60 (p =.022) and 180 min (p =.001). Blood pressure did not change. Hunger ratings in PLA increased 30 (p =.05), 60 (p =.04), 90 (p =.02), and 180 min (p =.05) after ingestion when compared to PX200. PX200 increased energy expenditure (all p <.05) when compared to PLA. Rates of fat oxidation tended to increase 90 (p =.056) and 120 min (p =.066) in PX200 compared to PLA. Free fatty acids increased in PX300 compared to PLA (p =.002). Glycerol did not change. Ingestion of PX200 augmented energy expenditure and hunger ratings when compared to PLA without impacting hemodynamics or lipolysis. pubtype: Academic Journal doctype: equations & formulas research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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