پیش بینی لخته شدن خون بند ناف پیش از جمع آوری با کمک الگوریتم های یادگیری ماشین پیشرفته.

Background and Objectives Umbilical cord blood is a valuable source of stem cells used in transplants to treat various diseases including leukemia, lymphoma and genetic disorders. However, cord blood clotting during the collection process can reduce sample quality and quantity and impact its efficac...

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Publicado en:Scientific Journal of Iranian Blood Transfusion Organization Vol. 21; no. 2; pp. 151 - 160
Autores principales: امیر حسین اسمعیل, مریم عاملی, اشکان مزدگیر, ارد احمدی, مرتضی ضرابی
Formato: equations & formulas research tables/charts Journal Article
Publicado: Iranian Blood Transfusion Organization Research Center Summer2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Summer2024
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      pub: Iranian Blood Transfusion Organization Research Center
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        atl: پیش بینی لخته شدن خون بند ناف پیش از جمع آوری با کمک الگوریتم های یادگیری ماشین پیشرفته.
      aug:
        au:
          امیر حسین اسمعیل
          مریم عاملی
          اشکان مزدگیر
          ارد احمدی
          مرتضی ضرابی
        affil: دانشجوی دکترای مهندسی صنایع - دانشکده فنی و مهندسی دانشگاه خوارزمی - تهران - ایران.
      sug:
        subj:
          Cordocentesis
          Fetal Blood
          Blood Coagulation
          Machine Learning
          Algorithms
          Human
          Retrospective Design
          Umbilical Cord Blood Banks
          Models, Statistical
          Comparative Studies
          Descriptive Statistics
          Bioinformatics
          Multilayer Perceptrons
          Random Forest
      ab: Background and Objectives Umbilical cord blood is a valuable source of stem cells used in transplants to treat various diseases including leukemia, lymphoma and genetic disorders. However, cord blood clotting during the collection process can reduce sample quality and quantity and impact its efficacy in cord blood banking. This article aims to predict pre-collection cord blood clotting in donors using advanced machine learning techniques. Materials and Methods In this retrospective study, data was gathered using 928127 samples available in the fetal cord blood bank, and with using supervised machine learning classification algorithms, including decision tree, naïve Bayes, K-Nearest Neighbors, Support vector machine, Random forest, Majority voting and Multilayer perceptron, prediction of cord blood clotting was performed on the Royan cord blood bank database and their performance was compared using evaluation metrics such as Accuracy, Precision, Recall, and F1 Score. Results In this study, the algorithm accuracy of Decision Tree was 0.80, Naive Bayes was 0.63, KNearest Neighbors was 0.83, Support Vector Machine was 0.65, Random Forest was 0.84, Majority Voting Classifier was 0.81, and Multilayer Perceptron was 0.74. Conclusions In this study, the performance of Random Forest and K-Nearest Neighbors algorithms demonstrated the best accuracy showing that machine learning algorithms can predict prenatal cord blood clotting with high accuracy which can help prevent sampling of clotted specimens in order to reduce costs and storage problems.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: Persian
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