Identifying the nature of episodic memory deficits in Major Depressive Disorder using a Real-World What-Where-When task.
Deficits in episodic memory have been reported in various psychiatric conditions, including Major Depressive Disorder (MDD). Many widely used episodic memory tests do not have the ability to distinguish between impaired memory of separate components of a real-life event (e.g., what happened, where i...
| Publicado en: | Memory Vol. 32; no. 7; pp. 924 - 935 |
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| Autores principales: | , , , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Aug2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=179172057&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 179172057 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09658211 BAY jtl: Memory issn: 09658211 maglogo: N pubinfo: dt: Aug2024 vid: 32 iid: 7 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 179172057 178290579 179172057 179172057 10.1080/09658211.2024.2371110 179172057 ppf: 924 ppct: 11 formats: tig: atl: Identifying the nature of episodic memory deficits in Major Depressive Disorder using a Real-World What-Where-When task. aug: au: Foka, Kyriaki Hunt, Hannah Constantinescu, Simona Choudhury, Tahsina Walker, Thomas J. Black-Dominique, Amber Lai, Daniel Bhoopathy, Raja Sanderson, Olivia Wray, Lauren McAllister-Williams, R. Hamish Gallagher, Peter Smulders, Tom V. affil: Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK sug: subj: Depression Complications Memory Disorders Psychosocial Factors Episodic Memory Task Performance and Analysis Funding Source Human Male Female Adolescence Adult Middle Age Aged Aged, 80 and Over Descriptive Statistics Linear Regression Chi Square Test Neuropsychological Tests Memory Adolescent: 13-18 years Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: Deficits in episodic memory have been reported in various psychiatric conditions, including Major Depressive Disorder (MDD). Many widely used episodic memory tests do not have the ability to distinguish between impaired memory of separate components of a real-life event (e.g., what happened, where it happened and when), and impaired binding of such real-life features. To address this issue, a naturalistic, real-world What-Where-When memory task was employed to assess the nature of episodic memory impairments in MDD. A validation study established that the task is sensitive to age-related episodic memory changes, and that intentional encoding does not invalidate the task. The main study then compared the performance of patients with depression and control participants on the intentionally encoded WWW task. Patients with MDD presented an overall episodic memory impairment arising from deficits in object memory and the ability to bind objects to temporal context. Taken together, our study confirms the episodic memory impairment in MDD, by providing evidence of deficient object memory and reduced ability to bind temporal context to objects in patients. Our naturalistic WWW task presents a promising approach for thorough identification of the nature of episodic memory impairments, under a real-world environment, in various conditions, including MDD. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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