Impact of Vitamin D Status and Nutrition on the Occurrence of Long Bone Fractures Due to Falls in Elderly Subjects in the Vojvodina Region of Serbia.

Bone fractures are a significant public health issue among elderly subjects. This study examines the impact of diet and vitamin D status on the risk of long bone fractures due to falls in elderly subjects in Vojvodina, Serbia. Conducted at the University Clinical Center of Vojvodina in autumn/winter...

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Publicado en:Nutrients Vol. 16; no. 16; pp. 2702 - 2732
Autores principales: Gvozdenović, Nemanja, Šarac, Ivana, Ćorić, Andrijana, Karan, Saša, Nikolić, Stanislava, Ždrale, Isidora, Milešević, Jelena
Formato: research tables/charts Journal Article
Publicado: MDPI Aug2024
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Impact of Vitamin D Status and Nutrition on the Occurrence of Long Bone Fractures Due to Falls in Elderly Subjects in the Vojvodina Region of Serbia.
      aug:
        au:
          Gvozdenović, Nemanja
          Šarac, Ivana
          Ćorić, Andrijana
          Karan, Saša
          Nikolić, Stanislava
          Ždrale, Isidora
          Milešević, Jelena
        affil: Faculty of Medicine, University of Novi Sad, 21137 Novi Sad, Serbia
      sug:
        subj:
          Femoral Fractures Risk Factors
          Accidental Falls In Old Age
          Vitamin D Blood
          Nutrition
          Risk Assessment
          Human
          Serbia
          Female
          Male
          Aged
          Case Control Studies
          Sample Size Determination
          Socioeconomic Factors
          Life Style
          Anthropometry
          Food Intake
          Frailty Syndrome
          Calcium, Dietary
          Dietary Proteins
          Dairy Products
          Eggs
          Fish
          Logistic Regression
          Analysis of Covariance
          Mann-Whitney U Test
          Spearman's Rank Correlation Coefficient
          ROC Curve
          Data Analysis Software
          T-Tests
          Funding Source
          Descriptive Statistics
          Aged: 65+ years
          Female
          Male
      ab: Bone fractures are a significant public health issue among elderly subjects. This study examines the impact of diet and vitamin D status on the risk of long bone fractures due to falls in elderly subjects in Vojvodina, Serbia. Conducted at the University Clinical Center of Vojvodina in autumn/winter 2022–2023, the study included 210 subjects >65 years: 105 (F: 80/M: 15) with long bone fractures due to falls and 105 (F: 80/M: 15) controls. Groups were similar regarding age and BMI. Dietary intakes (by two 24-h recalls) and serum vitamin D levels were analyzed. The fracture group had a significantly lower median daily vitamin D intake (1.4 μg/day vs. 5.8 μg/day), intake of calcium, energy, proteins, fats, fibers, dairy products, eggs, fish, edible fats/oils, and a higher intake of sweets (p < 0.001 for all). Serum vitamin D levels were significantly lower in the fracture group (40.0 nmol/L vs. 76.0 nmol/L, p < 0.001). Logistic regression identified serum vitamin D as the most important protective factor against fractures, and ROC curve analysis indicated that serum vitamin D levels > 50.5 nmol/L decreased fracture risk. Nutritional improvements (increased intake of vitamin D and protein sources such as fish, eggs, and dairy), increased sun exposure, and routine vitamin D supplementation during winter are advised.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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