Development and internal validation of an artificial intelligence-assisted bowel sounds auscultation system to predict early enteral nutrition-associated diarrhoea in acute pancreatitis: a prospective observational study.

Aims/Background An artificial intelligence-assisted prediction model for enteral nutrition-associated diarrhoea (ENAD) in acute pancreatitis (AP) was developed utilising data obtained from bowel sounds auscultation. This model underwent validation through a single-centre, prospective observational s...

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Publicado en:British Journal of Hospital Medicine (17508460) Vol. 85; no. 8; pp. 1 - 16
Autores principales: Liu, Chengcheng, Wu, Li, Xu, Rui, Jiang, Zhiwei, Xiao, Xiaoping, Song, Nian, Jin, Qianhong, Dai, Zhengxiang
Formato: pictorial research tables/charts Journal Article
Publicado: Mark Allen Holdings Limited Aug2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2024
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        10.12968/hmed.2024.0120
        179360649
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        atl: Development and internal validation of an artificial intelligence-assisted bowel sounds auscultation system to predict early enteral nutrition-associated diarrhoea in acute pancreatitis: a prospective observational study.
      aug:
        au:
          Liu, Chengcheng
          Wu, Li
          Xu, Rui
          Jiang, Zhiwei
          Xiao, Xiaoping
          Song, Nian
          Jin, Qianhong
          Dai, Zhengxiang
        affil: School of Nursing, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China
      sug:
        subj:
          Pancreatitis Diagnosis
          Diarrhea Diagnosis
          Diarrhea Epidemiology
          Diarrhea Risk Factors
          Artificial Intelligence
          Gastrointestinal Motility
          Auscultation Methods
          Systems Development
          Internal Validity
          Prediction Models
          Enteral Nutrition Methods
          Decision Making, Clinical
          Risk Assessment
          Predictive Value of Tests
          Human
          Male
          Female
          Adult
          Middle Age
          Aged
          Prospective Studies
          Nonexperimental Studies
          Univariate Statistics
          Logistic Regression
          Algorithms
          Sensitivity and Specificity
          ROC Curve
          Confidence Intervals
          Construct Validity
          China
          Clinical Assessment Tools
          Descriptive Statistics
          Funding Source
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Aims/Background An artificial intelligence-assisted prediction model for enteral nutrition-associated diarrhoea (ENAD) in acute pancreatitis (AP) was developed utilising data obtained from bowel sounds auscultation. This model underwent validation through a single-centre, prospective observational study. The primary objective of the model was to enhance clinical decision-making by providing a more precise assessment of ENAD risk. Methods The study enrolled patients with AP who underwent early enteral nutrition (EN). Real-time collection and analysis of bowel sounds were conducted using an artificial intelligence bowel sounds auscultation system. Univariate analysis, multicollinearity analysis, and logistic regression analysis were employed to identify risk factors associated with ENAD. The random forest algorithm was utilised to establish the prediction model, and partial dependence plots were generated to analyse the impact of risk factors on ENAD risk. Validation of the model was performed using the optimal model Bootstrap resampling method. Predictive performance was assessed using accuracy, sensitivity, specificity, positive predictive value, negative predictive value, and an area under the receiver operating characteristic (ROC) curve. Results Among the 133 patients included in the study, the incidence of ENAD was 44.4%. Six risk factors were identified, and the model's accuracy was validated through Bootstrap iterations. The prediction accuracy of the model was 81.10%, with a sensitivity of 84.30% and a specificity of 77.80%. The positive predictive value was 82.60%, and the negative predictive value was 80.10%. The area under the ROC curve was 0.904 (95% confidence interval: 0.817–0.997). Conclusion The artificial intelligence bowel sounds auscultation system enhances the assessment of gastrointestinal function in AP patients undergoing EN and facilitates the construction of an ENAD predictive model. The model demonstrates good predictive efficacy, offering an objective basis for precise intervention timing in ENAD management.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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