Explainable Artificial Intelligence for Early Prediction of Pressure Injury Risk.

Background: Hospital-acquired pressure injuries (HAPIs) have a major impact on patient outcomes in intensive care units (ICUs). Effective prevention relies on early and accurate risk assessment. Traditional risk-assessment tools, such as the Braden Scale, often fail to capture ICU-specific factors,...

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Publicado en:American Journal of Critical Care Vol. 33; no. 5; pp. 373 - 382
Autores principales: Alderden, Jenny, Johnny, Jace, Brooks, Katie R., Wilson, Andrew, Yap, Tracey L., Zhao, Yunchuan, van der Laan, Mark, Kennerly, Susan
Formato: CEU research Journal Article
Publicado: American Association of Critical-Care Nurses Sep2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2024
      vid: 33
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      pub: American Association of Critical-Care Nurses
      place: Alisa Veijo, California
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        atl: Explainable Artificial Intelligence for Early Prediction of Pressure Injury Risk.
      aug:
        au:
          Alderden, Jenny
          Johnny, Jace
          Brooks, Katie R.
          Wilson, Andrew
          Yap, Tracey L.
          Zhao, Yunchuan
          van der Laan, Mark
          Kennerly, Susan
        affil: an associate professor at Boise State University in Boise, Idaho
      sug:
        subj:
          Pressure Ulcer Epidemiology
          Pressure Ulcer Psychosocial Factors
          Pressure Ulcer Risk Factors
          Risk Assessment Methods
          Early Diagnosis Methods
          Hospitals
          Prediction Models
          Intensive Care Units
          Dashboard Systems
          Artificial Intelligence, Generative
          Education, Continuing (Credit)
          Human
          Algorithms
          Braden Scale for Predicting Pressure Sore Risk
          Scales
          Health Services Accessibility
          Hospitalization
          Privacy and Confidentiality
          Machine Learning Methods
          Critical Care
          Sensitivity and Specificity
          Outcomes (Health Care)
          Male
          Female
          Middle Age
          Aged
          Random Forest
          Descriptive Statistics
          ROC Curve
          Data Analysis Software
          Logistic Regression
          Oxygenation
          Perfusion
          Decision Making
          Retrospective Design
          Massachusetts
          Record Review
          Quality of Health Care
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Background: Hospital-acquired pressure injuries (HAPIs) have a major impact on patient outcomes in intensive care units (ICUs). Effective prevention relies on early and accurate risk assessment. Traditional risk-assessment tools, such as the Braden Scale, often fail to capture ICU-specific factors, limiting their predictive accuracy. Although artificial intelligence models offer improved accuracy, their "black box" nature poses a barrier to clinical adoption. Objective: To develop an artificial intelligence–based HAPI risk-assessment model enhanced with an explainable artificial intelligence dashboard to improve interpretability at both the global and individual patient levels. Methods: An explainable artificial intelligence approach was used to analyze ICU patient data from the Medical Information Mart for Intensive Care. Predictor variables were restricted to the first 48 hours after ICU admission. Various machine-learning algorithms were evaluated, culminating in an ensemble "super learner" model. The model's performance was quantified using the area under the receiver operating characteristic curve through 5-fold cross-validation. An explainer dashboard was developed (using synthetic data for patient privacy), featuring interactive visualizations for in-depth model interpretation at the global and local levels. Results: The final sample comprised 28 395 patients with a 4.9% incidence of HAPIs. The ensemble super learner model performed well (area under curve = 0.80). The explainer dashboard provided global and patient-level interactive visualizations of model predictions, showing each variable's influence on the risk-assessment outcome. Conclusion: The model and its dashboard provide clinicians with a transparent, interpretable artificial intelligence–based risk-assessment system for HAPIs that may enable more effective and timely preventive interventions.
      pubtype: Academic Journal
      doctype:
        CEU
        research
        Journal Article
      ougenre: Article
    language: English
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