Trajectories of pain and their associations with long-term cognitive decline in older adults: evidence from two longitudinal cohorts.

Background Pain is a dynamic experience that varies over time, but it remains unknown whether trajectories of pain are associated with subsequent cognitive decline. The purpose of this study was to identify distinct trajectories of pain presence and activity-limiting pain and investigate their longi...

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Publicado en:Age & Ageing Vol. 53; no. 8; pp. 1 - 9
Autores principales: He, Zijun, Li, Gege, Chen, Zhi, Hu, Zihang, Wang, Qingwei, Huang, Guozhi, Luo, Qinglu
Formato: Artículo
Publicado: Oxford University Press / USA Aug2024
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Oxford University Press / USA
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        atl: Trajectories of pain and their associations with long-term cognitive decline in older adults: evidence from two longitudinal cohorts.
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        au:
          He, Zijun
          Li, Gege
          Chen, Zhi
          Hu, Zihang
          Wang, Qingwei
          Huang, Guozhi
          Luo, Qinglu
        affil:
          Department of Rehabilitation Medicine, The Tenth Affiliated Hospital of Southern Medical University (Dongguan People's Hospital) , Dongguan, China
          Dongguan Experimental Centre for Sports Rehabilitation Research , Dongguan, China
          Department of Rehabilitation Medicine, Zhujiang Hospital, Southern Medical University , Guangzhou, China
          School of Rehabilitation Medicine, Southern Medical University , Guangzhou, China
          Rehabilitation Department, Dongguan Key Specialty of Traditional Chinese Medicine , Dongguan, China
      su:
        England
        Executive function
        Age distribution
        Pain
        Memory
        Aging
        Old age
        Cognition disorder risk factors
        Risk assessment
        Mental orientation
        Descriptive statistics
        Longitudinal method
        Geriatric assessment
        Data analysis software
        Confidence intervals
        Physical activity
        Time
      sug:
        subj:
          Executive function
          Age distribution
          Pain
          Memory
          Aging
          Old age
          England
          Cognition disorder risk factors
          Risk assessment
          Mental orientation
          Descriptive statistics
          Longitudinal method
          Geriatric assessment
          Data analysis software
          Confidence intervals
          Physical activity
          Time
      keyword:
        activity-limiting pain
        cognition
        cognitive decline
        cognitive impairment
        older adult
        older people
        pain
        pain presence
        pain trajectories
        activity-limiting pain
        cognition
        cognitive decline
        cognitive impairment
        older adult
        older people
        pain
        pain presence
        pain trajectories
      ab: Background Pain is a dynamic experience that varies over time, but it remains unknown whether trajectories of pain are associated with subsequent cognitive decline. The purpose of this study was to identify distinct trajectories of pain presence and activity-limiting pain and investigate their longitudinal associations with the rate of subsequent cognitive decline in older adults. Methods A total of 5685 participants from the English Longitudinal Study of Ageing (ELSA) and 7619 participants from the Health and Retirement Study (HRS) were included. Pain presence trajectories were identified over eight years in the ELSA and 10 years in the HRS, while trajectories of activity-limiting pain were identified over 10 years in the HRS. We utilised linear mixed-effects models to investigate the long-term relationship between pain trajectories and the rate of cognitive decline across various domains, including memory, orientation, executive function and global cognition. Results Three pain presence trajectories were identified. Moderate-increasing and high-stable groups exhibited steeper declines in global cognition than the low-stable group. Furthermore, individuals in the moderate-increasing group experienced a more rapid decline in executive function, while the high-stable group showed a faster decline in orientation function. Two trajectories of activity-limiting pain were identified, with the moderate-increasing group experiencing a faster decline in orientation function and global cognition. Conclusions The trajectories of both pain presence and activity-limiting pain are linked to the rate of subsequent cognitive decline among older people. Interventions for specific pain trajectories might help to delay the decline rate of cognition in specific domains.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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