Cover Image
QR Code

Quantitative Analysis of Different Foveal Avascular Zone Metrics in Healthy and Diabetic Subjects.

The primary aim of this study was to assess the size and shape of the Foveal Avascular Zone (FAZ) in patients with type 2 diabetes mellitus compared to healthy subjects. The study used 80 OCTA images from the FAZID dataset. The FAZ size was measured by its area, perimeter, and maximum/minimum Feret...

Full description

Published in:Diabetology Vol. 5; no. 3; pp. 246 - 255
Main Author: Sijilmassi, Ouafa
Format: equations & formulas pictorial research tables/charts Journal Article
Published: MDPI Aug2024
Online Access:View this record in EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=179381148&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 179381148
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        26734540
        N1A2
      jtl: Diabetology
      issn: 26734540
      maglogo: N
    pubinfo:
      dt: Aug2024
      vid: 5
      iid: 3
      pid: 97109
      pub: MDPI
    artinfo:
      ui:
        179381148
        179381148
        179381148
        10.3390/diabetology5030019
        179381148
      ppf: 246
      ppct: 9
      formats:
      tig:
        atl: Quantitative Analysis of Different Foveal Avascular Zone Metrics in Healthy and Diabetic Subjects.
      aug:
        au: Sijilmassi, Ouafa
        affil: Department of Optics, Faculty of Optics and Optometry, Complutense University of Madrid, C/Arcos de Jalón, 118, 28037 Madrid, Spain
      sug:
        subj:
          Diabetes Mellitus, Type 2 Complications
          Diabetic Retinopathy Risk Factors
          Risk Assessment
          Retina Anatomy and Histology
          Retina Radiography
          Human
          Funding Source
          Male
          Female
          Adult
          Middle Age
          Aged
          Tomography, Optical Coherence
          Data Analysis Software
          Descriptive Statistics
          Quantitative Studies
          T-Tests
          Nonparametric Statistics
          Kruskal-Wallis Test
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: The primary aim of this study was to assess the size and shape of the Foveal Avascular Zone (FAZ) in patients with type 2 diabetes mellitus compared to healthy subjects. The study used 80 OCTA images from the FAZID dataset. The FAZ size was measured by its area, perimeter, and maximum/minimum Feret diameters. The shape was assessed using the axial ratio, circularity, roundness, and solidity. These metrics were calculated automatically using Matlab® R2020b. Statistical analysis was performed using SPSS statistical software version 28.0, with a p-value of less than 0.01 considered significant. The results showed that the FAZ area was significantly larger in diabetic eyes (mean = 0.50 mm2) compared to control eyes (mean = 0.37 mm2), with a p-value of less than 0.01. Both the maximum and minimum diameters of the FAZ were also significantly larger in diabetic groups compared to the control group. Parameters associated with FAZ's shape were significantly smaller in the diabetic groups than in the control group, except for the axial ratio. The main finding of this study is that diabetic eyes without clinically detectable diabetic retinopathy exhibit morphological changes and irregularities at the FAZ border.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N