[18F]AlF-NOTA-PCP2: a novel PET/CT tracer for enhanced PD-L1 heterogeneity imaging and comparative analysis with [18F]AlF-NOTA-WL12 in glioblastoma xenografts.

Purpose: The unsatisfactory efficacy of PD-L1 antibodies in glioblastoma (GBM) is largely due to the temporal and spatial heterogeneity of PD-L1 expression. Molecular imaging can enhance understanding of the tumor immune microenvironment and guide immunotherapy. However, highly sensitive imaging age...

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Detalles Bibliográficos
Publicado en:European Journal of Nuclear Medicine & Molecular Imaging Vol. 51; no. 11; pp. 3161 - 3176
Autores principales: Wang, Yong, Zhang, Yang, Chen, Yunhao, Wang, Shijie, Liu, Wei, Liu, Zhiguo, Hu, Man
Formato: Journal Article
Publicado: Springer Nature Sep2024
Acceso en línea:Ver este registro en EBSCOhost