Clinical Utility of LC-MS/MS for Blood Myo-Inositol in Patients with Acute Kidney Injury and Chronic Kidney Disease.

Background Diagnosing acute kidney injury (AKI) and chronic kidney disease (CKD) relies on creatinine, which lacks optimal diagnostic sensitivity. The kidney-specific proximal tubular enzyme myo-inositol oxygenase (MIOX) catalyzes the conversion of myo-inositol (MI) to D-glucuronic acid. We hypothes...

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Bibliographic Details
Published in:Clinical Chemistry Vol. 70; no. 9; pp. 1172 - 1182
Main Authors: Omosule, Catherine L, Blair, Connor J, Herries, Elizabeth, Zaydman, Mark A, Farnsworth, Christopher, Ladenson, Jack, Dietzen, Dennis J, Gaut, Joseph P
Format: Journal Article
Published: Oxford University Press / USA Sep2024
Online Access:View this record in EBSCOhost