An Automated Heart Shunt Recognition Pipeline Using Deep Neural Networks.

Automated recognition of heart shunts using saline contrast transthoracic echocardiography (SC-TTE) has the potential to transform clinical practice, enabling non-experts to assess heart shunt lesions. This study aims to develop a fully automated and scalable analysis pipeline for distinguishing hea...

Descripción completa

Detalles Bibliográficos
Publicado en:Journal of Digital Imaging Vol. 37; no. 4; pp. 1424 - 1440
Autores principales: Wang, Weidong, Zhang, Hongme, Li, Yizhen, Wang, Yi, Zhang, Qingfeng, Ding, Geqi, Yin, Lixue, Tang, Jinshan, Peng, Bo
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Aug2024
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=179554137&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 179554137
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        08971889
        DOQ
      jtl: Journal of Digital Imaging
      issn: 08971889
      maglogo: N
    pubinfo:
      dt: Aug2024
      vid: 37
      iid: 4
      pid: 237
      pub: Springer Nature
      place: New York, New York
    artinfo:
      ui:
        179554137
        179554137
        179554137
        10.1007/s10278-024-01047-4
        179554137
      ppf: 1424
      ppct: 16
      formats:
        fmt:
          – @attributes:
              type: T
          – @attributes:
              type: P
      tig:
        atl: An Automated Heart Shunt Recognition Pipeline Using Deep Neural Networks.
      aug:
        au:
          Wang, Weidong
          Zhang, Hongme
          Li, Yizhen
          Wang, Yi
          Zhang, Qingfeng
          Ding, Geqi
          Yin, Lixue
          Tang, Jinshan
          Peng, Bo
        affil: https://ror.org/03h17x602 School of Computer Science and Software Engineering, Southwest Petroleum University, Chengdu, Sichuan, China
      sug:
        subj:
          Heart Septal Defects, Atrial Ultrasonography
          Echocardiography Methods
          Neural Networks (Computer)
          Deep Learning
          Automation
          Human
          Algorithms
          Conceptual Framework
          Models, Theoretical
          Microparticles
          Sensitivity and Specificity
          Descriptive Statistics
          Funding Source
      ab: Automated recognition of heart shunts using saline contrast transthoracic echocardiography (SC-TTE) has the potential to transform clinical practice, enabling non-experts to assess heart shunt lesions. This study aims to develop a fully automated and scalable analysis pipeline for distinguishing heart shunts, utilizing a deep neural network–based framework. The pipeline consists of three steps: (1) chamber segmentation, (2) ultrasound microbubble localization, and (3) disease classification model establishment. The study's normal control group included 91 patients with intracardiac shunts, 61 patients with extracardiac shunts, and 84 asymptomatic individuals. Participants' SC-TTE images were segmented using the U-Net model to obtain cardiac chambers. The segmentation results were combined with ultrasound microbubble localization to generate multivariate time series data on microbubble counts in each chamber. A classification model was then trained using this data to distinguish between intracardiac and extracardiac shunts. The proposed framework accurately segmented heart chambers (dice coefficient = 0.92 ± 0.1) and localized microbubbles. The disease classification model achieved high accuracy, sensitivity, specificity, F1 score, kappa value, and AUC value for both intracardiac and extracardiac shunts. For intracardiac shunts, accuracy was 0.875 ± 0.008, sensitivity was 0.891 ± 0.002, specificity was 0.865 ± 0.012, F1 score was 0.836 ± 0.011, kappa value was 0.735 ± 0.017, and AUC value was 0.942 ± 0.014. For extracardiac shunts, accuracy was 0.902 ± 0.007, sensitivity was 0.763 ± 0.014, specificity was 0.966 ± 0.008, F1 score was 0.830 ± 0.012, kappa value was 0.762 ± 0.017, and AUC value was 0.916 ± 0.006. The proposed framework utilizing deep neural networks offers a fast, convenient, and accurate method for identifying intracardiac and extracardiac shunts. It aids in shunt recognition and generates valuable quantitative indices, assisting clinicians in diagnosing these conditions.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N