Diagnostic Performance of Artificial Intelligence in Detection of Hepatocellular Carcinoma: A Meta-analysis.

Due to the increasing interest in the use of artificial intelligence (AI) algorithms in hepatocellular carcinoma detection, we performed a systematic review and meta-analysis to pool the data on diagnostic performance metrics of AI and to compare them with clinicians' performance. A search in PubMed...

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Publicado en:Journal of Digital Imaging Vol. 37; no. 4; pp. 1297 - 1312
Autores principales: Salehi, Mohammad Amin, Harandi, Hamid, Mohammadi, Soheil, Shahrabi Farahani, Mohammad, Shojaei, Shayan, Saleh, Ramy R.
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Springer Nature Aug2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2024
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-024-01058-1
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        atl: Diagnostic Performance of Artificial Intelligence in Detection of Hepatocellular Carcinoma: A Meta-analysis.
      aug:
        au:
          Salehi, Mohammad Amin
          Harandi, Hamid
          Mohammadi, Soheil
          Shahrabi Farahani, Mohammad
          Shojaei, Shayan
          Saleh, Ramy R.
        affil: https://ror.org/01c4pz451 School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
      sug:
        subj:
          Carcinoma, Hepatocellular Diagnosis
          Artificial Intelligence
          Diagnosis, Computer Assisted
          Sensitivity and Specificity
          Liver Diseases Diagnosis
          Human
          Systematic Review
          Meta Analysis
          PubMed
          Descriptive Statistics
          Data Analysis Software
          Confidence Intervals
          Algorithms
          Liver Neoplasms Pathology
          Checklists
      ab: Due to the increasing interest in the use of artificial intelligence (AI) algorithms in hepatocellular carcinoma detection, we performed a systematic review and meta-analysis to pool the data on diagnostic performance metrics of AI and to compare them with clinicians' performance. A search in PubMed and Scopus was performed in January 2024 to find studies that evaluated and/or validated an AI algorithm for the detection of HCC. We performed a meta-analysis to pool the data on the metrics of diagnostic performance. Subgroup analysis based on the modality of imaging and meta-regression based on multiple parameters were performed to find potential sources of heterogeneity. The risk of bias was assessed using Multivariable Prediction Model for Individual Prognosis or Diagnosis (TRIPOD) and Prediction Model Study Risk of Bias Assessment Tool (PROBAST) reporting guidelines. Out of 3177 studies screened, 44 eligible studies were included. The pooled sensitivity and specificity for internally validated AI algorithms were 84% (95% CI: 81,87) and 92% (95% CI: 90,94), respectively. Externally validated AI algorithms had a pooled sensitivity of 85% (95% CI: 78,89) and specificity of 84% (95% CI: 72,91). When clinicians were internally validated, their pooled sensitivity was 70% (95% CI: 60,78), while their pooled specificity was 85% (95% CI: 77,90). This study implies that AI can perform as a diagnostic supplement for clinicians and radiologists by screening images and highlighting regions of interest, thus improving workflow.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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