Serum irisin and caspase-9 levels in adolescents with substance use disorder: a case-control study.
Background: During adolescence, individuals experience rapid changes in physical, cognitive, emotional, behavioral, and social aspects of their life. Due to certain risks which arise during the developmental period of adolescence, substance use and addiction are encountered as a public health proble...
| Publicado en: | Journal of Substance Use Vol. 29; no. 5; pp. 736 - 742 |
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| Autores principales: | , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Oct2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=179554922&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 179554922 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14659891 ILV jtl: Journal of Substance Use issn: 14659891 maglogo: Y pubinfo: dt: Oct2024 vid: 29 iid: 5 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 179554922 163109134 179554922 179554922 10.1080/14659891.2023.2202765 179554922 ppf: 736 ppct: 6 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Serum irisin and caspase-9 levels in adolescents with substance use disorder: a case-control study. aug: au: Kara, Aziz Can, Ümmügülsüm Bağci, Zafer Esenkaya Usta, Zeynep affil: Department of Child and Adolescent Psychiatry, Afyonkarahisar Health Science University, Afyonkarahisar, Turkey sug: subj: Myokines Blood Adipokines Blood Caspases Blood Biological Markers Blood Sociodemographic Factors Substance Use Disorders Physiopathology Human Case Control Studies Muscle, Skeletal Hormones Blood Comparative Studies Education, Continuing Educational Status Child Adolescence Interviews Enzyme-Linked Immunosorbent Assay Data Analysis Software Chi Square Test T-Tests Mann-Whitney U Test Spearman's Rank Correlation Coefficient Male Female Descriptive Statistics Child: 6-12 years Adolescent: 13-18 years Male Female ab: Background: During adolescence, individuals experience rapid changes in physical, cognitive, emotional, behavioral, and social aspects of their life. Due to certain risks which arise during the developmental period of adolescence, substance use and addiction are encountered as a public health problem. Studies on biochemical parameters and puberty are limited. In this study, adolescents with substance use disorder were compared to healthy individuals in terms of sociodemographic characteristics and serum irisin and caspase-9 levels. Methods: The study group consisted of 32 adolescents with substance use disorder and the control group was comprised of 29 healthy adolescents. The sociodemographic characteristics and serum irisin and caspase-9 levels of the groups were compared. Results: The study group performed lower than the control group in terms of duration of education and continuing education. Serum caspase-9 levels were found to be significantly higher in the study group compared to the control group. There was no difference in irisin levels of the groups. Conclusions: It was determined that substance use negatively affects educational aspects and may also lead to certain destructive biological effects in adolescents. In order to reveal the effect of substance use on adolescents in more detail, studies with larger samples are needed. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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